Dr Rebecca Owens

Biology, Human Health Institute

Assistant Professor

Callan Building
2.30
(01) 708 3839/3140

Biography

Book Chapters

  Year Publication
2017 'Fungal Proteomics'
Doyle S. and Owens R.A. (2017) 'Fungal Proteomics' In: K. Kavanagh (eds). Fungi: Biology and Applications, 3rd Edition. United Kingdom: Wiley Blackwell. [Details]
2014 'Virulence characteristics of Aspergillus fumigatus'
Owens, RA; O' Keeffe, K; O' Hanlon KA; Gallagher, L; Doyle, S (2014) 'Virulence characteristics of Aspergillus fumigatus' In: Sullivan DJ; Moran, GP (eds). Human Pathogenic Fungi: New technologies and new insights. United Kingdom: Caister Academic Press. [Details]

Peer Reviewed Journals

  Year Publication
2021 'Proteomic profiling and glycomic analysis of the yeast cell wall in strains with Aflatoxin B1 elimination ability'
García-Béjar B.;Owens R.A.;Briones A.;Arévalo-Villena M. (2021) 'Proteomic profiling and glycomic analysis of the yeast cell wall in strains with Aflatoxin B1 elimination ability'. Environmental Microbiology, [DOI] [Details]
2021 'Effects of antifungal agents on the fungal proteome: informing on mechanisms of sensitivity and resistance'
Owens R.A.;Doyle S. (2021) 'Effects of antifungal agents on the fungal proteome: informing on mechanisms of sensitivity and resistance'. Expert Review of Proteomics, [DOI] [Details]
2021 'At the metal-metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin'
Traynor, A.M., Owens, R.A., Coughlin, C.M., Holton, M.C., Jones, G.W., Calera, J.A. and Doyle. S. (2021) 'At the metal-metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin'. MICROBIOL-SGM, [Details]
2021 'Hallmarks of Basidiomycete Soft- and White-Rot in Wood-Decay -Omics Data of Two Armillaria Species'
Sahu N;Merényi Z;Bálint B;Kiss B;Sipos G;Owens RA;Nagy LG; (2021) 'Hallmarks of Basidiomycete Soft- and White-Rot in Wood-Decay -Omics Data of Two Armillaria Species'. Microorganisms, 9 (1) [DOI] [Details]
2020 'The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence'
Ries LNA;Pardeshi L;Dong Z;Tan K;Steenwyk JL;Colabardini AC;Ferreira Filho JA;de Castro PA;Silva LP;Preite NW;Almeida F;de Assis LJ;Dos Santos RAC;Bowyer P;Bromley M;Owens RA;Doyle S;Demasi M;Hernández DCR;Netto LES;Pupo MT;Rokas A;Loures FV;Wong KH;Goldman GH; (2020) 'The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence'. PLoS Pathogens, 16 (7) [DOI] [Details]
2020 'Differential distribution and proteomic response ofSaccharomyces cerevisiaeand non-model yeast species to zinc'
Garcia-Bejar, B;Owens, RA;Briones, A;Arevalo-Villena, M (2020) 'Differential distribution and proteomic response ofSaccharomyces cerevisiaeand non-model yeast species to zinc'. Environmental Microbiology, [DOI] [Details]
2020 'Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence'
Scott, J;Sueiro-Olivares, M;Thornton, BP;Owens, RA;Muhamadali, H;Fortune-Grant, R;Thomson, D;Thomas, R;Hollywood, K;Doyle, S;Goodacre, R;Tabernero, L;Bignell, E;Amich, J (2020) 'Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence'. mBio, 11 [DOI] [Details]
2020 'Comparative genomic and proteomic analyses of three widespread phytophthora species: Phytophthora chlamydospora, phytophthora gonapodyides and phytophthora pseudosyringae'
McGowan J.;O’hanlon R.;Owens R.A.;Fitzpatrick D.A. (2020) 'Comparative genomic and proteomic analyses of three widespread phytophthora species: Phytophthora chlamydospora, phytophthora gonapodyides and phytophthora pseudosyringae'. Microorganisms, 8 (5) [DOI] [full-text] [Details]
2020 'Proteomic investigation of interhyphal interactions between strains of Agaricus bisporus'
O'Connor E.;Owens R.A.;Doyle S.;Amini A.;Grogan H.;Fitzpatrick D.A. (2020) 'Proteomic investigation of interhyphal interactions between strains of Agaricus bisporus'. Fungal Biology, 124 (6):579-591 [DOI] [Details]
2019 'Infective juveniles of entomopathogenic nematodes (Steinernema and Heterorhabditis) secrete ascarosides and respond to interspecific dispersal signals'
Hartley CJ;Lillis PE;Owens RA;Griffin CT; (2019) 'Infective juveniles of entomopathogenic nematodes (Steinernema and Heterorhabditis) secrete ascarosides and respond to interspecific dispersal signals'. Journal of Invertebrate Pathology, [DOI] [full-text] [Details]
2019 'Interrogation of Milk-Driven Changes to the Proteome of Intestinal Epithelial Cells by Integrated Proteomics and Glycomics'
Morrin S.;Owens R.;Le Berre M.;Gerlach J.;Joshi L.;Bode L.;Irwin J.;Hickey R. (2019) 'Interrogation of Milk-Driven Changes to the Proteome of Intestinal Epithelial Cells by Integrated Proteomics and Glycomics'. Journal of Agricultural and Food Chemistry, 67 (7):1902-1917 [DOI] [full-text] [Details]
2019 'Quantitative proteomic profiling of ochratoxin A repression in Penicillium nordicum by protective cultures'
Delgado J;Núñez F;Asensio MA;Owens RA; (2019) 'Quantitative proteomic profiling of ochratoxin A repression in Penicillium nordicum by protective cultures'. International Journal of Food Microbiology, 305 [DOI] [full-text] [Details]
2018 'Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in: Aspergillus fumigatus: A new direction in natural product functionality'
Saleh A.;Jones G.;Tinley F.;Delaney S.;Alabbadi S.;Fenlon K.;Doyle S.;Owens R. (2018) 'Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in: Aspergillus fumigatus: A new direction in natural product functionality'. Metallomics, 10 (6):854-866 [DOI] [full-text] [Details]
2018 'The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection'
Cullen L.;O’Connor A.;McCormack S.;Owens R.;Holt G.;Collins C.;Callaghan M.;Doyle S.;Smith D.;Schaffer K.;Fitzpatrick D.;McClean S. (2018) 'The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection'. Scientific Reports, 8 (1) [DOI] [full-text] [Details]
2017 'Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese'
Delgado J.;Owens R.;Doyle S.;Núñez F.;Asensio M. (2017) 'Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese'. Food Microbiology, 66 :1-10 [DOI] [full-text] [Details]
2017 'Functional investigation of iron-responsive microsomal proteins, including MirC, in Aspergillus fumigatus'
Mulvihill E.;Moloney N.;Owens R.;Dolan S.;Russell L.;Doyle S. (2017) 'Functional investigation of iron-responsive microsomal proteins, including MirC, in Aspergillus fumigatus'. Frontiers in Microbiology, 8 (MAR) [DOI] [full-text] [Details]
2016 'Antifungal proteins from moulds: analytical tools and potential application to dry-ripened foods'
Delgado J;Owens RA;Doyle S;Asensio MA;Núñez F; (2016) 'Antifungal proteins from moulds: analytical tools and potential application to dry-ripened foods'. Applied Microbiology and Biotechnology, 100 (16):6991-6700 [DOI] [full-text] [Details]
2017 'Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles'
Collins C;Hurley R;Almutlaqah N;O'Keeffe G;Keane TM;Fitzpatrick DA;Owens RA; (2017) 'Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles'. Microorganisms, 5 (3) [DOI] [full-text] [Details]
2017 'Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus'
Dolan S.K, Bock, T., Hering, V., Owens, R.A., Jones, G.W., Blankenfeldt W., Doyle S. (2017) 'Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus'. Open Biology, 7 [DOI] [full-text] [Details]
2016 'The iron-responsive microsomal proteome of Aspergillus fumigatus'
Moloney, NM*; Owens, RA*; Meleady, P; Henry, M; Dolan, SK; Mulvihill, E; Clynes, M; Doyle, S (2016) 'The iron-responsive microsomal proteome of Aspergillus fumigatus'. JOURNAL OF PROTEOMICS, 136 :99-111 [DOI] [full-text] [Details]
2016 'Proteomic analysis of Aspergillus fumigatus - clinical implications'
Moloney NM;Owens RA;Doyle S; (2016) 'Proteomic analysis of Aspergillus fumigatus - clinical implications'. Expert Review of Proteomics, [DOI] [Details]
2016 'Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP'
Delgado, J; Owens, RA; Doyle, S; Asensio, MA; Núñez, F (2016) 'Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP'. Applied Microbiology and Biotechnology, 100 (1):371-383 [DOI] [full-text] [Details]
2015 'Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus'
Owens, RA;O'Keeffe, G;Smith, EB;Dolan, SK;Hammel, S;Sheridan, KJ;Fitzpatrick, DA;Keane, TM;Jones, GW;Doyle, S (2015) 'Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus'. Eukaryotic Cell, 14 :941-957 [DOI] [full-text] [Details]
2015 'Impact of the antifungal protein PgAFP from Penicillium chrysogenum on the protein profile in Aspergillus flavus'
Delgado, J;Owens, RA;Doyle, S;Asensio, MA;Nunez, F (2015) 'Impact of the antifungal protein PgAFP from Penicillium chrysogenum on the protein profile in Aspergillus flavus'. Applied Microbiology and Biotechnology, 99 :8701-8715 [DOI] [full-text] [Details]
2015 'Biochemical Comparison of Commercial Selenium Yeast Preparations'
Fagan S.;Owens R.;Ward P.;Connolly C.;Doyle S.;Murphy R. (2015) 'Biochemical Comparison of Commercial Selenium Yeast Preparations'. Biological Trace Element Research, [DOI] [full-text] [Details]
2014 'A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus'
Owens, RA;Hammel, S;Sheridan, KJ;Jones, GW;Doyle, S (2014) 'A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus'. PLoS ONE, 9 [DOI] [full-text] [Details]
2014 'Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus'
Dolan, SK;Owens, RA;O'Keeffe, G;Hammel, S;Fitzpatrick, DA;Jones, GW;Doyle, S (2014) 'Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 21 :999-1012 [DOI] [full-text] [Details]
2014 'RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus'
O'Keeffe, G;Hammel, S;Owens, RA;Keane, TM;Fitzpatrick, DA;Jones, GW;Doyle, S (2014) 'RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus'. BMC Genomics, 15 [DOI] [full-text] [Details]
2012 'Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus'
O'Hanlon, KA;Margison, GP;Hatch, A;Fitzpatrick, DA;Owens, RA;Doyle, S;Jones, GW (2012) 'Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus'. Nucleic Acids Research, 40 :7806-7820 [DOI] [full-text] [Details]
2012 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'
Gallagher, L;Owens, RA;Dolan, SK;O'Keeffe, G;Schrettl, M;Kavanagh, K;Jones, GW;Doyle, S (2012) 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'. Eukaryotic Cell, 11 :1226-1238 [DOI] [full-text] [Details]

Conference Contributions

  Year Publication
2015 Chronic Burkholderia cenocepacia infection in cystic fibrosis: an analysis of the adaptations in sequential isolates from two patients.
Cullen, L;Owens, R;Callaghan, M;Doyle, S;Schaffer, K;McClean, S (2015) Chronic Burkholderia cenocepacia infection in cystic fibrosis: an analysis of the adaptations in sequential isolates from two patients. [Published Abstract], The 29th Annual North American Cystic Fibrosis Conference, Phoenix, AZ [Details]