Dr Rebecca Owens

Biology, Human Health Institute

Assistant Professor

Callan Building
2.30
(01) 708 3839/3140

Biography

Book Chapters

  Year Publication
2017 'Fungal Proteomics'
Doyle S. and Owens R.A. (2017) 'Fungal Proteomics' In: K. Kavanagh (eds). Fungi: Biology and Applications, 3rd Edition. United Kingdom: Wiley Blackwell. [Details]
2014 'Virulence characteristics of Aspergillus fumigatus'
Owens, RA; O' Keeffe, K; O' Hanlon KA; Gallagher, L; Doyle, S (2014) 'Virulence characteristics of Aspergillus fumigatus' In: Sullivan DJ; Moran, GP (eds). Human Pathogenic Fungi: New technologies and new insights. United Kingdom: Caister Academic Press. [Details]

Peer Reviewed Journals

  Year Publication
2018 'The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection'
Cullen L.;O’Connor A.;McCormack S.;Owens R.;Holt G.;Collins C.;Callaghan M.;Doyle S.;Smith D.;Schaffer K.;Fitzpatrick D.;McClean S. (2018) 'The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection'. Scientific Reports, 8 (1) [DOI] [Details]
2018 'Systems Impact of Zinc Chelation by the Epipolythiodioxopiperazine Dithiol Gliotoxin in Aspergillus fumigatus: A New Direction in Natural Product Functionality'
Saleh, A.A., Jones, G.W., Tinley, F.C., Delaney, S.F., Alabbadi, S., Fenlon K., Doyle, S. and Owens, R.A. (2018) 'Systems Impact of Zinc Chelation by the Epipolythiodioxopiperazine Dithiol Gliotoxin in Aspergillus fumigatus: A New Direction in Natural Product Functionality'. Metallomics, 10 :854-866 [DOI] [Details]
2017 'Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles'
Collins C;Hurley R;Almutlaqah N;O'Keeffe G;Keane TM;Fitzpatrick DA;Owens RA; (2017) 'Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles'. Microorganisms, 5 (3) [DOI] [IR Link] [Details]
2017 'Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese'
Delgado, J., Owens, R.A., Doyle, S., Nunez, F., Asensio M.A. (2017) 'Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese'. Food Microbiology, [DOI] [Details]
2017 'Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus'
Dolan S.K, Bock, T., Hering, V., Owens, R.A., Jones, G.W., Blankenfeldt W., Doyle S. (2017) 'Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus'. Open Biology, 7 [DOI] [IR Link] [Details]
2017 'Functional Investigation of Iron-Responsive Microsomal Proteins, Including MirC, in Aspergillus fumigatus'
Mulvihill, E.D., Moloney, N.M., Owens, R.A., Dolan, S.K., Russell, L. and Doyle S. (2017) 'Functional Investigation of Iron-Responsive Microsomal Proteins, Including MirC, in Aspergillus fumigatus'. Frontiers in Microbiology, 8 (418):1-15 [DOI] [IR Link] [Details]
2016 'The iron-responsive microsomal proteome of Aspergillus fumigatus'
Moloney, NM*; Owens, RA*; Meleady, P; Henry, M; Dolan, SK; Mulvihill, E; Clynes, M; Doyle, S (2016) 'The iron-responsive microsomal proteome of Aspergillus fumigatus'. JOURNAL OF PROTEOMICS, 136 :99-111 [DOI] [IR Link] [Details]
2016 'Antifungal proteins from moulds: Analytical tools and potential application to dry-ripened foods'
Delgado, J; Owens, RA; Doyle, S; Asensio, MA; Núñez, F (2016) 'Antifungal proteins from moulds: Analytical tools and potential application to dry-ripened foods'. Applied Microbiology and Biotechnology, 100 (16):6991-7000 [DOI] [Details]
2016 'Proteomic analysis of Aspergillus fumigatus - clinical implications'
Moloney NM;Owens RA;Doyle S; (2016) 'Proteomic analysis of Aspergillus fumigatus - clinical implications'. Expert Review of Proteomics, [DOI] [Details]
2016 'Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP'
Delgado, J; Owens, RA; Doyle, S; Asensio, MA; Núñez, F (2016) 'Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP'. Applied Microbiology and Biotechnology, 100 (1):371-383 [DOI] [IR Link] [Details]
2015 'Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus'
Owens, RA;O'Keeffe, G;Smith, EB;Dolan, SK;Hammel, S;Sheridan, KJ;Fitzpatrick, DA;Keane, TM;Jones, GW;Doyle, S (2015) 'Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus'. Eukaryotic Cell, 14 :941-957 [DOI] [IR Link] [Details]
2015 'Impact of the antifungal protein PgAFP from Penicillium chrysogenum on the protein profile in Aspergillus flavus'
Delgado, J;Owens, RA;Doyle, S;Asensio, MA;Nunez, F (2015) 'Impact of the antifungal protein PgAFP from Penicillium chrysogenum on the protein profile in Aspergillus flavus'. Applied Microbiology and Biotechnology, 99 :8701-8715 [DOI] [IR Link] [Details]
2015 'Biochemical Comparison of Commercial Selenium Yeast Preparations'
Fagan S.;Owens R.;Ward P.;Connolly C.;Doyle S.;Murphy R. (2015) 'Biochemical Comparison of Commercial Selenium Yeast Preparations'. Biological Trace Element Research, [DOI] [IR Link] [Details]
2014 'A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus'
Owens, RA;Hammel, S;Sheridan, KJ;Jones, GW;Doyle, S (2014) 'A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus'. PLoS ONE, 9 [DOI] [IR Link] [Details]
2014 'Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus'
Dolan, SK;Owens, RA;O'Keeffe, G;Hammel, S;Fitzpatrick, DA;Jones, GW;Doyle, S (2014) 'Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 21 :999-1012 [DOI] [IR Link] [Details]
2014 'RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus'
O'Keeffe, G;Hammel, S;Owens, RA;Keane, TM;Fitzpatrick, DA;Jones, GW;Doyle, S (2014) 'RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus'. BMC Genomics, 15 [DOI] [IR Link] [Details]
2012 'Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus'
O'Hanlon, KA;Margison, GP;Hatch, A;Fitzpatrick, DA;Owens, RA;Doyle, S;Jones, GW (2012) 'Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus'. Nucleic Acids Research, 40 :7806-7820 [DOI] [IR Link] [Details]
2012 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'
Gallagher, L;Owens, RA;Dolan, SK;O'Keeffe, G;Schrettl, M;Kavanagh, K;Jones, GW;Doyle, S (2012) 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'. Eukaryotic Cell, 11 :1226-1238 [DOI] [IR Link] [Details]

Conference Contributions

  Year Publication
2015 Chronic Burkholderia cenocepacia infection in cystic fibrosis: an analysis of the adaptations in sequential isolates from two patients.
Cullen, L;Owens, R;Callaghan, M;Doyle, S;Schaffer, K;McClean, S (2015) Chronic Burkholderia cenocepacia infection in cystic fibrosis: an analysis of the adaptations in sequential isolates from two patients. [Published Abstract], The 29th Annual North American Cystic Fibrosis Conference, Phoenix, AZ [Details]