Prof Kay Ohlendieck

Biology, Human Health Institute

Professor

Callan
2.33
(01) 708 3842

Biography

Education: 1980-1985 Diplom in Biology (M.Sc.), University of Konstanz, Germany; 1985-1989 Ph.D. in Biochemistry, University College Cork; Positions: 1989-1991 Postdoctoral fellow, University of Iowa, Iowa City; 1992-1994, State University of New York, Stony Brook; 1994-2002, College Lecturer, University College Dublin; 2002, Senior Lecturer in Pharmacology, University College Dublin; Since 2002: Professor and Chair, Department of Biology, National University of Ireland, Maynooth. 2011: D.Sc. for published work (NUI).

Book Chapters

  Year Publication
2013 'Gel electrophoresis-based proteomics of senescent tissues'
Carberry S, Ohlendieck K. (2013) 'Gel electrophoresis-based proteomics of senescent tissues' In: Methods in Molecular Biology, Vol. 1048. [Details]
2012 'Proteomic analysis of dystrophic muscle'
Lewis C, Doran P, Ohlendieck K. (2012) 'Proteomic analysis of dystrophic muscle' In: Methods in Molecular Biology, Vol. 798. [Details]
2010 'Role of chaperones in dystrophic and senescent muscle fibres'
Donoghue, P., Doran, P. and Ohlendieck, K. (2010) 'Role of chaperones in dystrophic and senescent muscle fibres' In: Handbook of Nutritional Biochemistry. New York: Nova Science Publisher. [Details]
2010 'Biochemical and proteomic profiling of key metabolic enzymes in aging skeletal muscle'
Donoghue, P., Doran, P. and Ohlendieck, K. (2010) 'Biochemical and proteomic profiling of key metabolic enzymes in aging skeletal muscle' In: Handbook of Nutritional Biochemistry. New York: Nova Science Publishers. [Details]
2009 'Centrifugation (revised)'
Ohlendieck, K. (2009) 'Centrifugation (revised)' In: Principles and Techniques of Biochemistry and Molecular Biology. Cambridge, UK: Cambridge University Press. [Details]
2005 'Centrifugation'
Ohlendieck, K.  (2005) 'Centrifugation' In: Principles and Techniques of Biochemistry and Molecular Biology. Cambridge: Cambridge University Press. [Details]
2004 'Extraction of membrane proteins'
Ohlendieck, K.  (2004) 'Extraction of membrane proteins' In: Methods in Molecular Biology, Vol. 244. Springer. [Details]
2004 'Purification of membrane proteins'
Ohlendieck, K.  (2004) 'Purification of membrane proteins' In: Methods in Molecular Biology, Vol. 244. Springer. [Details]
2004 'Removal of detergent from protein fractions'
Ohlendieck, K.  (2004) 'Removal of detergent from protein fractions' In: Methods in Molecular Biology, Vol. 244. Springer. [Details]

Peer Reviewed Journals

  Year Publication
2013 'Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research'
Carberry, S., Zweyer, M., Swandulla, D., Ohlendieck, K. (2013) 'Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research'. BIOLOGY, 2 :1438-1464 [full-text] [Details]
2010 'DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue'
Donoghue P, Staunton L, Mullen E, Manning G, Ohlendieck K. (2010) 'DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue'. JOURNAL OF PROTEOMICS, 73 :1441-1453 [full-text] [Details]
2010 'Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Protein'
Lewis C, Jockusch H, Ohlendieck K. (2010) 'Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Protein'. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2010 [full-text] [Details]
2007 'Proteomic profiling of pathological and aged skeletal muscle fibres by peptide mass fingerprinting'
Doran, P., P. Donoghue, K. O'Connell, J. Gannon and K. Ohlendieck. (2007) 'Proteomic profiling of pathological and aged skeletal muscle fibres by peptide mass fingerprinting'. International Journal of Molecular Medicine, 19 :547-564 [full-text] [Details]
2007 'Aging skeletal muscle shows a drastic increase in the small heat shock proteins alphaB-crystallin/HspB5 and cvHsp/HspB7'
Doran, P., J. Gannon, K. O’Connell and K. Ohlendieck.  (2007) 'Aging skeletal muscle shows a drastic increase in the small heat shock proteins alphaB-crystallin/HspB5 and cvHsp/HspB7'. European Journal of Cell Biology, 86 :629-640 [full-text] [Details]
2007 'Oligomerisation of sarcoplasmic reticulum Calcium-ATPase monomers from skeletal muscle'
Schreiber, D. and K. Ohlendieck.  (2007) 'Oligomerisation of sarcoplasmic reticulum Calcium-ATPase monomers from skeletal muscle'. Protein and Peptide Letters, 14 :219-226 [Details]
2007 'Proteomic profiling of animal models mimicking skeletal muscle disorders'
Doran, P., J. Gannon, K. O’Connell and K. Ohlendieck.  (2007) 'Proteomic profiling of animal models mimicking skeletal muscle disorders'. Proteomics - Clinical Applications, 1 :1169-1184 [full-text] [Details]
2005 'Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation. '
Donoghue, P., P. Doran, P. Dowling and K. Ohlendieck. (2005) 'Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation. '. Biochimica et Biophysica Acta - Proteins and Proteomics, 1752 :166-176 [full-text] [Details]
2005 'Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto–Kakizaki rat'
Mulvey, C., Harno, E., Keenan, A. and Ohlendieck, K. (2005) 'Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto–Kakizaki rat'. European Journal of Cell Biology, 84 :867-883 [full-text] [Details]
2004 'Drastic reduction of sarcalumenin in Dp427-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy'
Dowling, P., Doran, P. and Ohlendieck, K. Biochem J. 379, 479-488 (2004). (2004) 'Drastic reduction of sarcalumenin in Dp427-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy'. Biochemical Journal, 379 :479-488 [full-text] [Details]
2004 'Increased sensitivity of the ryanodine receptor to halothane-induced oligomerisation in malignant hyperthermia-susceptible human skeletal muscle'
Glover, L., Heffron, J.J.A., and Ohlendieck, K. (2004) 'Increased sensitivity of the ryanodine receptor to halothane-induced oligomerisation in malignant hyperthermia-susceptible human skeletal muscle'. Journal of Applied Physiology, 96 :11-18 [full-text] [Details]
2004 'Illustration of skeletal muscle calsequestrin complex formation by cell overlay and two-dimensional blot overlay methodology'
Glover, L. and Ohlendieck, K. (2004) 'Illustration of skeletal muscle calsequestrin complex formation by cell overlay and two-dimensional blot overlay methodology'. BASIC AND APPLIED MYOLOGY, 14 :231-241 [full-text] [Details]
2004 'Subproteomics analysis of calcium-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle'
Doran, P., Dowling, P., Lohan, J., McDonnell, K. Poetsch, S., and Ohlendieck, K. (2004) 'Subproteomics analysis of calcium-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle'. European Journal of Biochemistry, 271 :3943-3952 [full-text] [Details]
2004 'Early effects of denervation on calcium-handling proteins in skeletal muscle'
Donoghue, P., Ribaric, S., Moran, V., Cebasek, B., Erzen, I., and Ohlendieck, K. (2004) 'Early effects of denervation on calcium-handling proteins in skeletal muscle'. International Journal of Molecular Medicine, 13 :767-772 [Details]
2004 'Drastic reduction in the luminal calcium-binding proteins calsequestrin and sarcalumenin in dystrophin-deficient cardiac muscle'
Lohan, J. and Ohlendieck, K. (2004) 'Drastic reduction in the luminal calcium-binding proteins calsequestrin and sarcalumenin in dystrophin-deficient cardiac muscle'. Biochimica et biophysica acta, 1689 :252-258 [full-text] [Details]
2003 'Persistent expression of the alpha-1S dihydropyridine receptor in aged human skeletal muscle: Implications for the excitation-contraction uncoupling hypothesis of sarcopenia'
Ryan, M., Butler-Browne, G., Erzen, I., Mouly, V., Thornell, L.-E., Wernig, A., and Ohlendieck, K. (2003) 'Persistent expression of the alpha-1S dihydropyridine receptor in aged human skeletal muscle: Implications for the excitation-contraction uncoupling hypothesis of sarcopenia'. International Journal of Molecular Medicine, 11 :425-434 [Details]

Conference Contributions

  Year Publication
2009 International Symposium of Molecular Medicine.
(2009) International Symposium of Molecular Medicine. [Oral Presentation], Proteomics of diabetes-induced muscle weakness, Athens, Greece [Details]
2009 XXXVIII European Muscle Conference.
(2009) XXXVIII European Muscle Conference. [Oral Presentation], Proteomics of muscular dystrophy, Lille, France [Details]
2009
Dr. Simon Whitehall (2009) [Visiting and guest lecturers hosted], The HIRA Histone Chaperone: A Global Regulator of, Institute of Cell and Molecular Biosciences, Newca, Science, Biology [Details]
2009
Dr Paul Bowyer (2009) [Visiting and guest lecturers hosted], Death, Taxes and Aspergillus - The Inevitability o, School of Translational Medicine, University of Ma, Science, Biology [Details]
2009
Professor Elodie Ghedin (2009) [Visiting and guest lecturers hosted], The Genesis of Influenza Virus Diversity, Division of Infectious Diseases, University of Pit, Science, Biology [Details]
2009 American Association of Clinical Chemists Meeting.
(2009) American Association of Clinical Chemists Meeting. [Poster Presentation], Biomarker signature of age-related muscle weakness, Chicago, IL, USA [Details]
2009
Professor Rosemary O'Connor (2009) [Visiting and guest lecturers hosted], The Insulin-like Growth Factor System in Health an, Department of Biochemistry, University College Cor, Science, Biology [Details]
2009
Professor Channapatna S. Prakash (2009) [Visiting and guest lecturers hosted], Challenges in the Adoption of Agribiotechnology in, Dept. of Agricultural & Environmental Sciences, Tu, Science, Biology [Details]
2009
Dr. Clara Redondo (2009) [Visiting and guest lecturers hosted], Retinol Binding Protein Interactions, Marie Curie Laboratory for Membrane Proteins NUI M, Science, Biology [Details]
2009 Annual Meeting, Muscular Dystrophy Ireland.
(2009) Annual Meeting, Muscular Dystrophy Ireland. [Oral Presentation], Experimental exon skipping therapy, Dublin [Details]
2009
Dr. Thomas Ritter (2009) [Visiting and guest lecturers hosted], Gene- and Cell Therapeutic Applications for the Pr, REMEDI/NUI Galway, Science, Biology [Details]
2009
Dr. Ewen Mullins (2009) [Visiting and guest lecturers hosted], Are GM Crops Relevant to Ireland's Agriculture?, Biotechnology Centre, Teagasc Crops Research Centr, Science, Biology [Details]
2009
Dr. Brian Burke (2009) [Visiting and guest lecturers hosted], Targeted Genome Editing in Mammalian Cells Using E, Sigma Life Sciences, Dorset, UK, Science, Biology [Details]
2009
Professor Mike Lehane (2009) [Visiting and guest lecturers hosted], Tsetse Flies and Trypanosomes - Africa's Bane or A, Vector Group, Liverpool School of Tropical Medicin, Science, Biology [Details]
2009 1st Congress on Analytical Proteomics.
(2009) 1st Congress on Analytical Proteomics. [Oral Presentation], Proteomic profiling of muscle aging, Lisboa, Portugal [Details]
2009
Professor Thomas Ostenfeld Larsen (2009) [Visiting and guest lecturers hosted], Biotechnology and Analytical Natural Product Chemi, Department of Systems Biology, Center for Microbia, Science, Biology [Details]
2009
Dr. Adam Claridge-Chang (2009) [Visiting and guest lecturers hosted], Writing Memories with Light-Addressable Reinforcem, Nuffield Department of Clinical Medicine, Universi, Science, Biology [Details]
2009
Professor Elodie Ghedin (2009) [Visiting and guest lecturers hosted], The filaria /Brugia malayi/ and its Wolbachia endo, Division of Infectious Diseases, University of Pit, Science, Biology [Details]
2009
Professor John Parkinson (2009) [Visiting and guest lecturers hosted], HBiological Networks: Just How do They Evolve?, Hospital for the Sick Children, Toronto, Canada, Science, Biology [Details]
2009 European Seating Symposium 2009.
(2009) European Seating Symposium 2009. [Oral Presentation], Proteomic profiling of x-linked muscular dystrophy, Dublin [Details]
2009
Dr. Sandra O'Neill (2009) [Visiting and guest lecturers hosted], The Immunosuppressive Action of Helminth Molecules, School of Nursing, DCU, Science, Biology [Details]

Book Review

  Year Publication
2013 On-membrane digestion technology for muscle proteomics.
Ohlendieck, K. (2013) On-membrane digestion technology for muscle proteomics. Book Review [Details]
2013 Proteomics of exercise-induced skeletal muscle adaptations.
Ohlendieck, K. (2013) Proteomics of exercise-induced skeletal muscle adaptations. Book Review [Details]
2012 Proteomic profiling of skeletal muscle plasticity.
Ohlendieck, K. (2012) Proteomic profiling of skeletal muscle plasticity. Book Review [Details]
2012 Organelle proteomics in skeletal muscle biology.
Ohlendieck, K. (2012) Organelle proteomics in skeletal muscle biology. Book Review [Details]
2007 Proteomic profiling of aged and pathological skeletal muscle.
Doran, P., Gannon, J., O’Connell, K. and Ohlendieck, K. (2007) Proteomic profiling of aged and pathological skeletal muscle. Book Review [Details]