Prof John P. Lowry

Chemistry, Human Health Institute

Gaeilge agus fáilte

Professor

MAP Lodge
5
(01) 708 4639

Biography

  • 2012-Present: Professor/Chair of Chemistry, Maynooth University
  • 2007-2012: Adjunct Professor of Pharmacology, School of Biomolecular and Biomedical Sciences, UCD
  • 2006-2012: Professor/Chair and Head of Chemistry, National University of Ireland, Maynooth
  • 2004-2006: Lecturer & Examiner in Pharmacology/Principal Investigator: School of Biomolecular and Biomedical Sciences (Dept. of Pharmacology), UCD
  • 1998-2004: Lecturer & Examiner in Chemistry, National University of Ireland, Maynooth
  • 1996-1998: European Commission Marie Curie Fellow, UCD & University of Oxford
  • 1994-1996: European Commission Marie Curie Fellow, University of Oxford
  • 1992-1994: Forbairt Post-Doctoral Research Associate, UCD.
  • 1988-1992: PhD, Chemistry, UCD
  • 1984-88: BSc (Honours) Chemistry, UCD

Research Interests

• Neurochemistry
• Analytical Chemistry
• Electrochemistry
• Pharmacology
• Behavioural Neuroscience
• Sensors and Biosensors
• Brain Microdialysis

Books

  Year Publication
2002 Journal of Neuroscience Methods.
O'Connor W.T., O'Connor J.J., Lowry J.P. and O'Neill R.D. (2002) Journal of Neuroscience Methods. : Elsevier Science B.V. [Details]
2001 Monitoring Molecules in Neuroscience.
(2001) Monitoring Molecules in Neuroscience. : Univeristy College Dublin Press. [Details]

Book Chapters

  Year Publication
2006 'Real-time monitoring of brain extracellular lactate'
Bolger, F.B., Serra, P.A., Dalton, M., O’Neill, R.D., Fillenz, M. and Lowry, J.P. (2006) 'Real-time monitoring of brain extracellular lactate' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2006 'Development of a catalase-based biosensor for the detection of endogenous hydrogen peroxide in brain extracellular fluid'
O’Brien, K.B., Killoran, S.J., O’Neill, R.D. and Lowry, J.P. (2006) 'Development of a catalase-based biosensor for the detection of endogenous hydrogen peroxide in brain extracellular fluid' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2006 'Designing a polymer/enzyme composite biosensor suitable for clinical monitoring of glutamate in brain ECF'
Kirwan, S.M., Rocchita, G., Lowry, J.P. and O’Neill, R.D. (2006) 'Designing a polymer/enzyme composite biosensor suitable for clinical monitoring of glutamate in brain ECF' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2006 'Development of a microelectrochemical sensor for monitoring brain nitric oxide in vivo'
Finnerty, N.J., Bolger, F.B. and Lowry, J.P. (2006) 'Development of a microelectrochemical sensor for monitoring brain nitric oxide in vivo' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2006 'Significant enhancement of glutamate biosensor sensitivity using a polycation-modified polymer/enzyme composite sensing layer'
Rocchitta, G., McMahon, C.P. Serra, P.A., Kirwan, S.M., Bolger, F.B., Lowry, J.P. and O’Neill, R.D. (2006) 'Significant enhancement of glutamate biosensor sensitivity using a polycation-modified polymer/enzyme composite sensing layer' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2006 'Development of a biosensor for the in vivo detection of brain extracellular D-Aspartate'
Sheridan E., Obrenovich, T.P. Tedeschi, G. and Lowry, J.P. (2006) 'Development of a biosensor for the in vivo detection of brain extracellular D-Aspartate' In: In Monitoring Molecules in Neuroscience. Cagliara, Italy: University of Cagliari Press. [Details]
2006 'An oxygen electrode for monitoring behaviour in freely moving rats'
Fillenz, M., McHugh, S.B. Lowry, J.P. Bannerman, D.M. and Rawlins, J.N.P. (2006) 'An oxygen electrode for monitoring behaviour in freely moving rats' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari Press. [Details]
2005 'Neuroanalytical Chemistry In Vivo Using Biosensors'
Lowry, J.P. and O'Neill, R.D. (2005) 'Neuroanalytical Chemistry In Vivo Using Biosensors' In: Encyclopedia of Sensors. California: American Scientific Publishers. [Details]
2003 'An investigation of Pt electrodes for in vivo monitoring of brain oxygen'
Bolger, F.B. and Lowry, J.P. (2003) 'An investigation of Pt electrodes for in vivo monitoring of brain oxygen' In: Monitoring Molecules in Neuroscience. Stockholm: Karolinska University Press. [Details]
2003 'Utilisation of polystyrene as an immobilisation matrix in the construction of a lactate biosensor for real-time in vivo monitoring'
Dalton, M. and Lowry, J.P. (2003) 'Utilisation of polystyrene as an immobilisation matrix in the construction of a lactate biosensor for real-time in vivo monitoring' In: Monitoring Molecules in Neuroscience. Stockholm: Karolinska University Press. [Details]
2003 'An investigation of TTF:TCNQ biosensors for in vivo monitoring under O2 compromised conditions'
Jago, J.M. and Lowry, J.P. (2003) 'An investigation of TTF:TCNQ biosensors for in vivo monitoring under O2 compromised conditions' In: Monitoring Molecules in Neuroscience. Stockholm: Karolinska University Press. [Details]
2003 'A Microelectrochemical Sensor for Real-Time Monitoring of Regional Cerebral Blood Flow'
Lowry, J.P. and Finn, T. (2003) 'A Microelectrochemical Sensor for Real-Time Monitoring of Regional Cerebral Blood Flow' In: Monitoring Molecules in Neuroscience. Stockholm: Karolinska University Press. [Details]
2001 'A polystyrene-based glucose biosensor for in vivo neurochemical analysis'
Dalton, M and Lowry, J.P. (2001) 'A polystyrene-based glucose biosensor for in vivo neurochemical analysis' In: Monitoring Molecules in Nevroscience. Dublin: University Press, University College Dublin. [Details]
2001 'Interference in biosensor detection of brain glutamate in vivo: possible role of endogenous ECF hydrogen peroxide'
Lowry, J.P., Ryan, MR. and O'Neill, R.D. (2001) 'Interference in biosensor detection of brain glutamate in vivo: possible role of endogenous ECF hydrogen peroxide' In: Monitoring Molecules in Neuroscience. Dublin: University Press, University College Dublin. [Details]
2001 'Biosensors for in vivo monitoring: a comparison of the interference rejection characteristics of poly(o-phenylenediamine) and Nafion'
Dunne, S.O., Brown, P.O. and Lowry, J.P. (2001) 'Biosensors for in vivo monitoring: a comparison of the interference rejection characteristics of poly(o-phenylenediamine) and Nafion' In: Monitoring Molecules in Neuroscience. Dublin: University Press, University College Dublin. [Details]
2001 'In vivo determination of activation-dependent metabolic coupling'
Fillenz, M., Lowry, J.P., Boutelle, M.G. and Miele, M. (2001) 'In vivo determination of activation-dependent metabolic coupling' In: Neuroenergetics: Relevance for functional brain imaging. Human Frontier Science Program, Workshop XI, Strasbourg; Vol. 11. Strasbourg: Human Frontier Science Programme. [Details]
2001 'Brain energy metabolism: an investigation using real-time amperometric sensors'
Lowry, J.P. and Fillenz, M. (2001) 'Brain energy metabolism: an investigation using real-time amperometric sensors' In: Monitoring Molecules in Neuroscience. Dublin: University Press, University College Dublin. [Details]
2001 'Oxygen dependence of a enzyme/polymer biosensor designed for brain glucose detection in vivo'
Dixon, B.M., Lowry, J.P. and O'Neill, R.D. (2001) 'Oxygen dependence of a enzyme/polymer biosensor designed for brain glucose detection in vivo' In: Monitoring Molecules in Neuroscience. Dublin: University Press, University College Dublin. [Details]
2000 'Voltammetry In Vivo for Chemical Analysis of the Living Brain'
O'Neill, R.D. and Lowry, J.P. (2000) 'Voltammetry In Vivo for Chemical Analysis of the Living Brain' In: Encyclopedia of Analytical Chemistry. Instrumentation and Applications. Chichester, UK: John Wiley and Sons. [Details]
1999 'Brain Ascorbic Acid: Influence of Voltammetric Technique on Recorded Signal'
Lowry, JJP., Harford, C. J., (JNeill, R.D. and Fillenz, M. (1999) 'Brain Ascorbic Acid: Influence of Voltammetric Technique on Recorded Signal' In: Monitoring Molecules in Neuroscience. Newark: University Press, The State University of New Jersey. [Details]
1999 'A glutamate biosensor with high oxygen tolerance for neurochemical analysis in vivo'
Dixon, B.M., Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1999) 'A glutamate biosensor with high oxygen tolerance for neurochemical analysis in vivo' In: Monitoring Molecules in Neuroscience. Newark: University Press, The State University of New Jersey. [Details]
1999 'Permselective polymers in the design of biosensors for chemical analysis in vivo'
Craig, J.D., Ryan, M.R., Lowry, J.P. and R.D. O'Neill. (1999) 'Permselective polymers in the design of biosensors for chemical analysis in vivo' In: Monitoring Molecules in Neuroscience. Newark: University Press, The State University of New Jersey. [Details]
1999 'Nafion-modified carbon paste biosensors for in vivo neurochemical analysis: the effect of surfactant'
Dalton, M. and Lowry, J.P. (1999) 'Nafion-modified carbon paste biosensors for in vivo neurochemical analysis: the effect of surfactant' In: Monitoring Molecules in Newoscience. Newark: University Press, The State University of New Jersey. [Details]
1998 'Determination of brain extracellular glucose in vivo with an implanted biosensor'
Lowry, J.P. and Fillenz, M. (1998) 'Determination of brain extracellular glucose in vivo with an implanted biosensor' In: Neurochemistry. New York: Plenum Publishing Corporation. [Details]
1996 'Simultaneous real-time monitoring of glucose and oxygen in vivo'
Lowry, J.P. and Fillenz, M. (1996) 'Simultaneous real-time monitoring of glucose and oxygen in vivo' In: Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain. [Details]
1996 'Partial optimisation of a glutamate biosensor for neurochemical applications in vivo'
Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1996) 'Partial optimisation of a glutamate biosensor for neurochemical applications in vivo' In: Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain. [Details]
1996 'A glucose biosensor: Real-time monitoring of extracellular glucose'
Lowry, J.P., Boutelle, M.G., O'Neill, R.D. and Fillenz, M. (1996) 'A glucose biosensor: Real-time monitoring of extracellular glucose' In: Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain. [Details]
1994 'Chronically implantable glucose electrode based on a polymer/enzyme composite'
Lowry, J.P. and O'Neill, R.D. (1994) 'Chronically implantable glucose electrode based on a polymer/enzyme composite' In: Monitoring Molecules in Neuroscience, Proceedings of the 6th International Conference on In Vivo Methods, Universities of Bordeaux I and II, Bordeaux. [Details]
1994 'Uric acid levels as an index of brain tissue condition during in vivo monitoring experiments'
Duff, A., Lowry, J.P. and O'Neill, R.D. (1994) 'Uric acid levels as an index of brain tissue condition during in vivo monitoring experiments' In: Monitoring Molecules in Neuroscience, Proceedings of the 6th International Conference on In Vivo Methods, Universities of Bordeaux I and II, Bordeaux. [Details]
1991 'Enhancement of the glucose to ascorbate response at glucose oxidase modified conducting organic salt electrodes'
Lowry, J.P. and O'Neill, R.D. (1991) 'Enhancement of the glucose to ascorbate response at glucose oxidase modified conducting organic salt electrodes' In: Monitoring Molecules in Neuroscience: Proceedings of the 5th International Conference on In Vivo Methods, University Centre for Pharmacy, Gronigen. [Details]

Peer Reviewed Journals

  Year Publication
2014 'Differential Contributions of Infralimbic Prefrontal Cortex and Nucleus Accumbens during Reward-Based Learning and Extinction'
Francois, J., Huxter, J., Conway, MW., Lowry, JP., Tricklebank, MD. and Gilmour, G. (2014) 'Differential Contributions of Infralimbic Prefrontal Cortex and Nucleus Accumbens during Reward-Based Learning and Extinction'. JOURNAL OF NEUROSCIENCE, 34 :596-607 [IR Link] [Details]
2013 'Hemodynamic responses in amygdala and hippocampus distinguish between aversive and neutral cues during Pavlovian fear conditioning in behaving rats'
McHugh, S.B., Marques-Smith, A., Li, J., Rawlins, J.N.P., Lowry, J.P., Conway, M.W., Gilmour, G., Tricklebank, M. and Bannerman, D.M. (2013) 'Hemodynamic responses in amygdala and hippocampus distinguish between aversive and neutral cues during Pavlovian fear conditioning in behaving rats'. EUROPEAN JOURNAL OF NEUROSCIENCE, 37 :498-507 [IR Link] [Details]
2013 'Simultaneous recording of hippocampal oxygen and glucose in real time using constant potential amperometry in the freely-moving rat'
Kealy, J., Bennett, R. and Lowry, J.P. (2013) 'Simultaneous recording of hippocampal oxygen and glucose in real time using constant potential amperometry in the freely-moving rat'. JOURNAL OF NEUROSCIENCE METHODS, 215 :110-120 [IR Link] [Details]
2013 'Variation in Serotonin Transporter Expression Modulates Fear-Evoked Hemodynamic Responses and Theta-Frequency Neuronal Oscillations in the Amygdala'
Barkus C, Line SJ, Huber A, Capitao L, Lima J, Jennings K, Lowry J, Sharp T, Bannerman DM, McHugh SB. (2013) 'Variation in Serotonin Transporter Expression Modulates Fear-Evoked Hemodynamic Responses and Theta-Frequency Neuronal Oscillations in the Amygdala'. BIOLOGICAL PSYCHIATRY, 1 :1-1 [IR Link] [Details]
2013 'Highly selective and stable microdisc biosensors for L-glutamate monitoring'
Govindarajan, S., McNeil, C.J., Lowry, J.P., McMahon, C.P. and ONeill, R.D. (2013) 'Highly selective and stable microdisc biosensors for L-glutamate monitoring'. SENSORS AND ACTUATORS B-CHEMICAL, 178 :606-614 [IR Link] [Details]
2013 'An investigation of hypofrontality in an animal model of schizophrenia using real-time microelectrochemical sensors for glucose, oxygen, and nitric oxide'
Finnerty, N.J., Bolger, F.B., Plsson, E. and Lowry, J.P. (2013) 'An investigation of hypofrontality in an animal model of schizophrenia using real-time microelectrochemical sensors for glucose, oxygen, and nitric oxide'. ACS CHEMICAL NEUROSCIENCE, 4 :825-831 [IR Link] [Details]
2013 'Continuous Real-Time in vivo Measurement of Cerebral Nitric Oxide Supports Theoretical Predictions of an Irreversible Switching in Cerebral ROS after Sufficient Exposure to External Toxins'
Finnerty, N.J., O'Riordan, S.L., Lowry, J.P., Cloutier, M., Wellstead, P. (2013) 'Continuous Real-Time in vivo Measurement of Cerebral Nitric Oxide Supports Theoretical Predictions of an Irreversible Switching in Cerebral ROS after Sufficient Exposure to External Toxins'. JOURNAL OF PARKINSON'S DISEASE, 3 :351-362 [IR Link] [Details]
2012 'A comparison of the effects of the dopamine partial agonists aripiprazole and (−)-3-PPP with quinpirole on stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry in vitro'
OConnor J.J. and Lowry J.P. (2012) 'A comparison of the effects of the dopamine partial agonists aripiprazole and (−)-3-PPP with quinpirole on stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry in vitro'. EUROPEAN JOURNAL OF PHARMACOLOGY, 686 :60-65 [IR Link] [Details]
2012 'Brain nitric oxide: Regional characterisation of a real-time microelectrochemical sensor'
Finnerty, N.J., ORiordan, S.L., Plsson, E. and Lowry, J.P. (2012) 'Brain nitric oxide: Regional characterisation of a real-time microelectrochemical sensor'. JOURNAL OF NEUROSCIENCE METHODS, 209 :13-21 [IR Link] [Details]
2012 'Changes in reward-related signals in the rat nucleus accumbens measured by in vivo oxygen amperometry are consistent with fMRI BOLD responses in man'
Francois, J., Conway, M.W. Lowry J.P., Tricklebank M. and Gilmour, G. (2012) 'Changes in reward-related signals in the rat nucleus accumbens measured by in vivo oxygen amperometry are consistent with fMRI BOLD responses in man'. NEUROIMAGE, 60 :2169-2181 [IR Link] [Details]
2011 'Close temporal coupling of neuronal activity and tissue oxygen responses in rodent whisker barrel cortex'
Li, J., Bravo, D.S., Upton, A.L., Gilmour, G., Tricklebank,M.D., Fillenz, M., Martin, C., Lowry, J.P., Bannerman, D.M. and McHugh, S.B. (2011) 'Close temporal coupling of neuronal activity and tissue oxygen responses in rodent whisker barrel cortex'. EUROPEAN JOURNAL OF NEUROSCIENCE, 34 :1983-1996 [IR Link] [Details]
2011 'In vivo characterisation of a Nafion®-modified Pt electrode for real-time nitric oxide monitoring in brain extracellular fluid'
Finnerty, N.J., O’Riordan, S.L., Brown, F.O., Serra, P.A., O’Neill, R.D. and Lowry, J.P. (2011) 'In vivo characterisation of a Nafion®-modified Pt electrode for real-time nitric oxide monitoring in brain extracellular fluid'. Analytical Methods, 4 :550-557 [DOI] [IR Link] [Details]
2010 'Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety'
McHugh, S.B., Fillenz, M., Lowry, J.P., Rawlins, N.P. and Bannerman, D.M. (2010) 'Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety'. European Journal of Neuroscience, 33 :322-337 [IR Link] [Details]
2010 'Real-time electrochemical monitoring of brain tissue oxygen: a surrogate for functional magnetic resonance imaging in rodents'
Lowry J.P., Griffin K., McHugh S.B., Lowe A.S., Tricklebank M. and Sibson N.R. (2010) 'Real-time electrochemical monitoring of brain tissue oxygen: a surrogate for functional magnetic resonance imaging in rodents'. NEUROIMAGE, 52 :549-555 [IR Link] [Details]
2009 'Nitric oxide monitoring in brain extracellular fluid: Characterisation of Nafion-modified Pt electrodes in vitro and in vivo'
Brown, F.O., N.J. Finnerty and J.P. Lowry (2009) 'Nitric oxide monitoring in brain extracellular fluid: Characterisation of Nafion-modified Pt electrodes in vitro and in vivo'. ANALYSIS, 134 :2012-2020 [IR Link] [Details]
2009 'Increased Cortical Nitric Oxide Release After Phencyclidine Administration'
Pålsson, E., N. Finnerty, K. Fejgin, D. Klamer, C. Wass, L. Svensson and J. Lowry (2009) 'Increased Cortical Nitric Oxide Release After Phencyclidine Administration'. SYNAPSE, 63 :1083-1088 [IR Link] [Details]
2009 'Development of a voltammetric technique for monitoring brain dopamine metabolism: compensation for interference caused by DOPAC electrogenerated during homovanillic acid detection'
Al Mulla, I., J.P. Lowry, P.A. Serra, and R.D. O'Neill (2009) 'Development of a voltammetric technique for monitoring brain dopamine metabolism: compensation for interference caused by DOPAC electrogenerated during homovanillic acid detection'. ANALYST, 5 :893-898 [IR Link] [Details]
2009 'Prefrontal GABAB Receptor Activation Attenuates Phencyclidine-Induced Impairments of Prepulse Inhibition: Involvement of Nitric Oxide'
Fejgin, K., E. Pålsson, C. Wass, N. Finnerty, J. Lowry and D. Klamer (2009) 'Prefrontal GABAB Receptor Activation Attenuates Phencyclidine-Induced Impairments of Prepulse Inhibition: Involvement of Nitric Oxide'. NEUROPSYCHOPHARMACOLOGY, 34 :1673-1684 [Details]
2009 'Remediation of chromium(VI) at polypyrrole-coated titanium'
Earley, S.T., B.E. Alcock, J.P. Lowry and C.B. Breslin. (2009) 'Remediation of chromium(VI) at polypyrrole-coated titanium'. JOURNAL OF APPLIED ELECTROCHEMISTRY, 27 :1251-1257 [IR Link] [Details]
2009 'Biotelemetric Monitoring of Brain Neurochemistry in Conscious Rats Using Microsensors and Biosensors'
Calia, G., G. Rocchitta, R. Migheli, G. Puggioni, Y. Spissu, G. Bazzu, V. Mazzarello, J.P. Lowry, R.D. O'Neill, M.S. Desole and P.A. Serra. (2009) 'Biotelemetric Monitoring of Brain Neurochemistry in Conscious Rats Using Microsensors and Biosensors'. SENSORS, 9 :2511-2523 [IR Link] [Details]
2009 'Real-time monitoring of brain tissue oxygen using a miniaturized biotelemetric device implanted in freelymoving rats'
Bazzu, G., G. Puggioni, S. Dedola, G. Calia, G. Rocchitta, R. Migheli, M.S. Desole, J.P. Lowry, R.D. O'Neill, P. A. Serra (2009) 'Real-time monitoring of brain tissue oxygen using a miniaturized biotelemetric device implanted in freelymoving rats'. ANALYTICAL CHEMISTRY, 81 :323-330 [IR Link] [Details]
2009 'Combined fMRI and metabolic voltammetry in vivo: understanding the neurochemical basis of functional imaging signals'
Sibson, N., McHugh, S., and Lowry, J.P. (2009) 'Combined fMRI and metabolic voltammetry in vivo: understanding the neurochemical basis of functional imaging signals'. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 29 :S613-S614 [Details]
2009 'An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements'
Cloutier, M., F.B. Bolger, J.P. Lowry and P. Wellstead (2009) 'An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements'. JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 27 :391-414 [IR Link] [Details]
2009 'Contributions by a novel edge effect to thh permselectivity of an electrosynthesized polymer for microbiosensor applications'
Rothwell,S.A., M.E. Kinsella, Z.M. Zain, Pier A. Serra, G. Rocchitta, J.P. Lowry and R.D. O’Neill (2009) 'Contributions by a novel edge effect to thh permselectivity of an electrosynthesized polymer for microbiosensor applications'. ANALYTICAL CHEMISTRY, :3911-3918 [IR Link] [Details]
2008 'Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo'
O'Neill, R.D., Lowry, J.P., Rocchitta, G. , McMahon, C.P. and Serra, P.A. (2008) 'Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo'. TRAC-TRENDS IN ANALYTICAL CHEMISTRY   , 27 :78-88 [IR Link] [Details]
2007 'Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity'
McMahon, C.P., Rocchitta, G., Kirwan, S.M., Killoran, S.J., Serra, P.A. Lowry J.P. and O’Neill R.D. (2007) 'Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity'. 22 :1466-1473 [IR Link] [Details]
2007 'Animal models for the assessment of cognitive dysfunctions in schizophrenia: focus on the nitric oxide pathway'
Klamer, D.S., E.N. Palsson, C.E. Wass, K.W. Fejgin, N.J. Finnerty, J.P. Lowry, J.A. Engel and L.I. Svensson (2007) 'Animal models for the assessment of cognitive dysfunctions in schizophrenia: focus on the nitric oxide pathway'. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 17 :S188-S189 [Details]
2007 'Modifications of poly(o-phenylenediamine) permselective layer on Pt-Ir for biosensor application in neurochemical monitoring'
Kirwan, S.M., G. Rocchitta, C.P. McMahon, J.D. Craig, S.J. Killoran, K.B. O'Brien, P.A. Serra, J.P. Lowry and R.D. O'Neill (2007) 'Modifications of poly(o-phenylenediamine) permselective layer on Pt-Ir for biosensor application in neurochemical monitoring'. SENSORS, 7 :420-437 [IR Link] [Details]
2007 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'
Serra, P.A., G. Rocchitta, G. Bazzu, A. Manca, G.M. Puggioni, J.P. Lowry and R.D. O'Neill. (2007) 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'. SENSORS AND ACTUATORS B-CHEMICAL, 122 :118-126 [IR Link] [Details]
2007 'Development of a distributed, fully automated, bidirectional telemetry system for amperometric microsensor and biosensor applications'
Rocchitta, G., Migheli, R., Dedola, S., Calia, G., Desole, M.S., Miele, E., Lowry, J.P., O'Neill R.D. and Serra, P.A. (2007) 'Development of a distributed, fully automated, bidirectional telemetry system for amperometric microsensor and biosensor applications'. SENSORS AND ACTUATORS B-CHEMICAL, 126 :700-709 [IR Link] [Details]
2007 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'
Serra, P.A. Rocchitta, G., Bazzu, G., Manca, A., Puggioni, G.M., Lowry J.P. and O’Neill R.D. (2007) 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'. Sensors and Actuators, B: Chemical, 122 :118-126 [IR Link] [Details]
2007 'Biosensor for the neurotransmitter L-glutamic acid: Development and characterisation'
Kinsella, M.E., Lowry, J.P. and O'Neill, R.D. (2007) 'Biosensor for the neurotransmitter L-glutamic acid: Development and characterisation'. JOURNAL OF NEUROCHEMISTRY, 102 (Suppl. 1) [Details]
2006 'The efficiency of immobilised glutamate oxidase decreases with surface enzyme loading: an electrostatic effect, and reversal by a polycation significantly enhances biosensor sensitivity'
Lowry, J.P., Mc Mahon, C.P., Rocchitta, G., Serra, P., Kirwan, S.M. and O'Neill, R.D. (2006) 'The efficiency of immobilised glutamate oxidase decreases with surface enzyme loading: an electrostatic effect, and reversal by a polycation significantly enhances biosensor sensitivity'. ANALYST, 131 :68-72 [IR Link] [Details]
2006 'Control of the oxygen dependence of an implantable polymer/enzyme composite biosensor for glutamate'
McMahon, C.P., Rocchitta, G., Serra, P.A., Kirwan, S.M., Lowry, J.P. & O'Neill, R.D. (2006) 'Control of the oxygen dependence of an implantable polymer/enzyme composite biosensor for glutamate'. Journal of Analytical Chemistry, 78 :2352-2359 [IR Link] [Details]
2005 'Formation of Adherent Polypyrrole Coatings on Ti and Ti-6Al-4V Alloy'
Earley, S.T., Dowling, D.P., Lowry, J.P. and Breslin, C.B. (2005) 'Formation of Adherent Polypyrrole Coatings on Ti and Ti-6Al-4V Alloy'. Synthetic Metals, 148 :111-118 [IR Link] [Details]
2005 'Calibration of NO sensors for In Vivo Voltammetry: Laboratory synthesis of NO and the use of UV-visible spectroscopy in determining stock concentrations'
Brown, F.O., Finnerty, N.J., Bolger, F.B., Millar, J. and Lowry, J.P. (2005) 'Calibration of NO sensors for In Vivo Voltammetry: Laboratory synthesis of NO and the use of UV-visible spectroscopy in determining stock concentrations'. Analytical and Bioanalytical Chemistry, 381 :964-971 [IR Link] [Details]
2005 'Brain Tissue Oxygen: In Vivo Monitoring using Carbon Paste Electrodes'
Bolger, F.B. and Lowry, J.P. (2005) 'Brain Tissue Oxygen: In Vivo Monitoring using Carbon Paste Electrodes'. Sensors, 5 :473-487 [IR Link] [Details]
2004 'Monitoring Real-time Metabolite Trafficking in the Brain using Microelectrochemical Biosensors'
Lowry, J.P. (2004) 'Monitoring Real-time Metabolite Trafficking in the Brain using Microelectrochemical Biosensors'. ANNALS OF THE MARIE CURIE FELLOWSHIP ASSOCIATION, III :92-97 [IR Link] [Details]
2003 'Microelectrochemical Sensors for In Vivo Brain Analysis: An Investigation of Procedures for Modifying Pt Electrodes Using Nafion®'
Brown, F.O. and Lowry, J.P. (2003) 'Microelectrochemical Sensors for In Vivo Brain Analysis: An Investigation of Procedures for Modifying Pt Electrodes Using Nafion®'. The Analyst, 128 :700-705 [IR Link] [Details]
2002 'Oxygen dependence of an enzyme/polymer biosensor for monitoring brain glucose in vivo'
Dixon, B.M., Lowry, J.P. and O’Neill, R.D. (2002) 'Oxygen dependence of an enzyme/polymer biosensor for monitoring brain glucose in vivo'. Journal of Neuroscience Methods, 119 :135-142 [IR Link] [Details]
2002 'In Vivo Methods: Monitoring Molecules in Neuroscience'
O’Connor, W.T., O’Connor, J.J., Lowry, J.P. and O’Neill, R.D. (2002) 'In Vivo Methods: Monitoring Molecules in Neuroscience'. JOURNAL OF NEUROSCIENCE METHODS, 119 :105-107 [IR Link] [Details]
2001 'The role of astrocytes in neuronal metabolism: Real time monitoring of metabolic trafficking'
Lowry, J.P. and Fillenz, M. (2001) 'The role of astrocytes in neuronal metabolism: Real time monitoring of metabolic trafficking'. Journal of Neurochemistry, 78 (Suppl. 1) [Details]
2001 'In Vivo Evidence Supporting Compartmentalisation in Brain Energy Metabolism'
Lowry, J.P., Dunne, S.O. and Fillenz, M. (2001) 'In Vivo Evidence Supporting Compartmentalisation in Brain Energy Metabolism'. 170 :103-104 [Details]
2001 'Real-Time Monitoring of Brain Energy Metabolism In Vivo using Microelectrochemical Sensors: The Effects of Anesthesia'
Lowry, J.P. and Fillenz, M. (2001) 'Real-Time Monitoring of Brain Energy Metabolism In Vivo using Microelectrochemical Sensors: The Effects of Anesthesia'. Bioelectrochemistry, 54 :39-47 [IR Link] [Details]
1999 'The role of astrocytes and noradrenaline in neuronal glucose metabolism'
Fillenz, M., Lowry, J.P., Boutelle, M.G. and Fray, A.E. (1999) 'The role of astrocytes and noradrenaline in neuronal glucose metabolism'. ACTA PHYSIOLOGICA SCANDINAVICA, 167 :275-284 [IR Link] [Details]
1998 'Monitoring brain chemistry in vivo: Voltammetric techniques, sensors and behavioral applications'
O'Neill, R.D., Lowry, J.P. and Mas, M. (1998) 'Monitoring brain chemistry in vivo: Voltammetric techniques, sensors and behavioral applications'. CRITICAL REVIEWS IN NEUROBIOLOGY, 12 :69-127 [Details]
1998 'Behaviourally induced changes in ectracellular levels of brain glutamate monitored at 1 s resolution with an implanted biosensor'
Lowry, J.P., Ryan, M.R. and O'Neill, R.D. (1998) 'Behaviourally induced changes in ectracellular levels of brain glutamate monitored at 1 s resolution with an implanted biosensor'. Analytical Communications, 35 :87-89 [IR Link] [Details]
1998 'Continuous monitoring of extracellular glucose concentrations in the striatum of freely moving rats with an implanted glucose biosensor'
Lowry, J.P., CWeill, R.D., Boutelle, M.G. and Fillenz, M. (1998) 'Continuous monitoring of extracellular glucose concentrations in the striatum of freely moving rats with an implanted glucose biosensor'. Journal of Neurochemistry, 70 :391-396 [IR Link] [Details]
1998 'An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: In vivo characterization in the striatum of freely-moving rats'
Lowry, J.P., Miele, M., O'Neill, R.D., Boutelle, M.G. and Fillenz, M. (1998) 'An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: In vivo characterization in the striatum of freely-moving rats'. Journal of Neuroscience Methods, 79 :65-74 [IR Link] [Details]
1998 'The relation between local cerebral blood flow and extracellular glucose in rat striatum'
Lowry, J.P. and Fillenz, M. (1998) 'The relation between local cerebral blood flow and extracellular glucose in rat striatum'. Experimental Physiology, 83 :233-238 [IR Link] [Details]
1998 'Relation between local cerebral blood flow and extracellular glucose concentration in rat striatum during mild hypoxia and hyperoxia'
Lowry, J.P., Demestre, M. and Fillenz, M. (1998) 'Relation between local cerebral blood flow and extracellular glucose concentration in rat striatum during mild hypoxia and hyperoxia'. Developmental Neuroscience, 20 :52-58 [Details]
1998 'Studies of the source of glucose in the extracellular compartment of the rat brain'
Fillenz, M. and Lowry, J.P. (1998) 'Studies of the source of glucose in the extracellular compartment of the rat brain'. Developmental Neuroscience, 20 :365-368 [Details]
1997 'The source of extracellular brain glucose during neuronal activation: A biosensor study'
Lowry, J.P. and Fillenz, M. (1997) 'The source of extracellular brain glucose during neuronal activation: A biosensor study'. JOURNAL OF NEUROCHEMISTRY, 69 (Suppl.) [Details]
1997 'The effect of mild hypoxia and hyperoxia on local cerebral blood flow and brain extracellular glucose'
Fillenz, M. and Lowry, J.P. (1997) 'The effect of mild hypoxia and hyperoxia on local cerebral blood flow and brain extracellular glucose'. JOURNAL OF NEUROCHEMISTRY, 69 (Suppl.) [Details]
1997 'The source of extracellular brain glucose and its role in neuronal glycolysis'
Fillenz, M. and Lowry, J.P. (1997) 'The source of extracellular brain glucose and its role in neuronal glycolysis'. JOURNAL OF NEUROCHEMISTRY, 69 (Suppl.) [Details]
1997 'The relation between local cerebral blood flow and extracellular glucose concentration in rat striatum'
Lowry, J.P. and Fillenz, M. (1997) 'The relation between local cerebral blood flow and extracellular glucose concentration in rat striatum'. Physiology, 499P [IR Link] [Details]
1997 'Evidence for uncoupling of oxygen and glucose utilisation during neuronal activation in rat striatum'
Lowry, J.P. and Fillenz, M. (1997) 'Evidence for uncoupling of oxygen and glucose utilisation during neuronal activation in rat striatum'. Physiology, 498 :497-501 [IR Link] [Details]
1997 'A biosensor for neurotransmitter L-glutamic acid designed for efficient use of L-glutamate oxidase and effective rejection of interference'
Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1997) 'A biosensor for neurotransmitter L-glutamic acid designed for efficient use of L-glutamate oxidase and effective rejection of interference'. The Analyst, 112 :1419-1424 [IR Link] [Details]
1997 'Measurement of brain tissue oxygen at a carbon paste electrode can serve as an index of increases in regional cerebral blood flow'
Lowry, J.P., Boutelle, M.G. and Fillenz, M. (1997) 'Measurement of brain tissue oxygen at a carbon paste electrode can serve as an index of increases in regional cerebral blood flow'. Journal of Neuroscience Methods, 71 :177-182 [IR Link] [Details]
1996 'Characterisation of carbon paste electrodes in vitro for simultaneous amperometric measurement of changes in oxygen and ascorbic acid concentrations in vivo'
Lowry, J.P., Boutelle, M.G., O'Neill, R.D. and Fillenz, M. (1996) 'Characterisation of carbon paste electrodes in vitro for simultaneous amperometric measurement of changes in oxygen and ascorbic acid concentrations in vivo'. The Analyst, 121 :761-766 [Details]
1996 'In vivo glucose measurements in rat striatum with an implanted sensor'
Lowry, J.P. and Fillenz, M. (1996) 'In vivo glucose measurements in rat striatum with an implanted sensor'. JOURNAL OF NEUROCHEMISTRY, 66 (Suppl.2) [Details]
1994 'Characterization of glucose oxidase-modified poly(phenylenediamine)-coated electrodes in vitro and in vivo: Homogeneous interference by ascorbic acid in hydrogen peroxide detection'
Lowry, J.P., McAteer, K., El Attash, S.S., Duff, A. and O'Neill, R.D. (1994) 'Characterization of glucose oxidase-modified poly(phenylenediamine)-coated electrodes in vitro and in vivo: Homogeneous interference by ascorbic acid in hydrogen peroxide detection'. Journal of Analytical Chemistry, 66 :1754-1761 [IR Link] [Details]
1994 'Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: Implications for biomedical applications'
Lowry, J.P., McAteer, K., El Attash, S.S. and O'Neill, R.D. (1994) 'Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: Implications for biomedical applications'. Chemical Communications, 21 :2483-2484 [IR Link] [Details]
1993 'Partial characterization in vitro of glucose oxidase-modified poly(phenylenediamine)-coated electrodes for neurochemical analysis in vivo'
Lowry, J.P. and O'Neill, R.D. (1993) 'Partial characterization in vitro of glucose oxidase-modified poly(phenylenediamine)-coated electrodes for neurochemical analysis in vivo'. Electroanalysis, 6 :369-379 [Details]
1992 'Homogeneous mechanism of ascorbic acid interference in hydrogen peroxide detection at enzyme-modified electrodes'
Lowry, J.P. and O'Neill, R.D. (1992) 'Homogeneous mechanism of ascorbic acid interference in hydrogen peroxide detection at enzyme-modified electrodes'. Journal of Analytical Chemistry, 64 :453-456 [Details]
1992 'Strategies for reducing ascorbate interference at glucose oxidase modified conducting organic salt electrodes'
Lowry, J.P. and O'Neill, R.D. (1992) 'Strategies for reducing ascorbate interference at glucose oxidase modified conducting organic salt electrodes'. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 334 :183-194 [Details]
1991 'Anomalously high concentrations of striatal extracellular uric acid detected with chronically implanted probes: Implications for in vivo sampling techniques'
O'Neill, R.D., Gonzalez-Mora, J.L., Boutelle, M.G., Ormonde, D.E., Lowry, J.P., Duff, A., Fumero, B., Fillenz, M. and Mas, M. (1991) 'Anomalously high concentrations of striatal extracellular uric acid detected with chronically implanted probes: Implications for in vivo sampling techniques'. Journal of Neurochemistry, 57 :22-29 [Details]
1989 'Detection of brain extracellular uric acid - Dependance on probe size'
Lowry, J.P. and O'Neill, R.D. (1989) 'Detection of brain extracellular uric acid - Dependance on probe size'. Journal of Neuroscience Methods, 29 [Details]

Conference Contributions

  Year Publication
2016 Monitoring Molecules in Neuroscience:16th International Conference.
Michelle M. Doran; John P. Lowry (2016) Monitoring Molecules in Neuroscience:16th International Conference. [Poster Presentation], The Role of Oxidative Stress Manifestation in Parkinson's Disease, Gothenburg, Sweeden , 29-MAY-16 - 02-JUN-16 [Details]
2016 Monitoring Molecules in Neuroscience:16th International Conference.
Saidhbhe L. O'Riordan; John P. Lowry (2016) Monitoring Molecules in Neuroscience:16th International Conference. [Poster Presentation], Real-time electrochemical monitoring of physiological biomarkers: methods to investigate disorders of the brain and evaluate muscle tissue viability, Gothenburg, Sweeden , 29-JUL-17 - 02-JUN-16 [Details]
2014 14th International Conference on Oxidative Stress Reduction,Redox Homeostasis & Antioxidants.
Michelle M. Doran; John P. Lowry (2014) 14th International Conference on Oxidative Stress Reduction,Redox Homeostasis & Antioxidants. [Poster Presentation], Development of a Biosensor for the In-Vivo Detection of Superoxide, Paris, France , 12-JUN-14 - 13-JUN-14 [Details]
2009
Dr. Andrew Kellett (2009) [Visiting and guest lecturers hosted], Anti-Tumor Potential and Mechanistic Studies of New Copper (II) Complexes, Dublin IT, Science and Engineering, Chemistry [Details]
2009
Dr. Seán Doyle (2009) [Visiting and guest lecturers hosted], Proteome mining of Aspergillus fumigatus - smack at the interface of chemistry and genomics, NUIM, Science and Engineering, Chemistry [Details]
2009
Dr. Martyn Boutelle (2009) [Visiting and guest lecturers hosted], Electroanalytical Methods - Powerful tools to study the problem of brain injury in patients, Imperial College London, Science and Engineering, Chemistry [Details]
2009
Professor Carmel Breslin (2009) [Visiting and guest lecturers hosted], Conducting Polymers with Molecular Recognition Sites: Applications in Electrochemical Sensing, NUIM, Science and Engineering, Chemistry [Details]
2009
Professor Carmel Breslin (2009) [Visiting and guest lecturers hosted], Electroanalytical Methods coupled with Spectroscopy and Surface Analysis, NUIM, Science and Engineering, Chemistry [Details]
2009
Dr. Michael Lyons (2009) [Visiting and guest lecturers hosted], Redox and catalytic properties of carbon nanotube modified electrodes, Trinity College Dublin, Science and Engineering, Chemistry [Details]
2009
Dr. André Brodkorb (2009) [Visiting and guest lecturers hosted], From nano to macro food structures - the relevance of chemistry in food science, Teagasc Moorepark Food Research Centre, Science and Engineering, Chemistry [Details]
2009
Professor Philip Bartlett (2009) [Visiting and guest lecturers hosted], RSC Tilden Endowed Lecture: Using Electrochemical SERS to Discriminate Mutations in DNA, University of Southampton, Science and Engineering, Chemistry [Details]
2009
Dr. Isabel Rozas (2009) [Visiting and guest lecturers hosted], Versatile guanidinium-like compounds in medicinal chemistry, Trinity College Dublin, Science and Engineering, Chemistry [Details]
2009
Professor Edmond Magner (2009) [Visiting and guest lecturers hosted], Bioelectrochemistry and Biocatalysis in Nonaqueous media, University of Limerick, Science and Engineering, Chemistry [Details]
2009
Dr. Fintan Kelleher (2009) [Visiting and guest lecturers hosted], Flexibility in Organic and Medicinal Chemistry - Friend or Foe!!, IT Tallaght, Science and Engineering, Chemistry [Details]
2009
Dr. John O'Connor (2009) [Visiting and guest lecturers hosted], Real time measurement of dopamine and serotonin in brain tissue, UCD, Science and Engineering, Chemistry [Details]
2009
Professor Robert O'Neill (2009) [Visiting and guest lecturers hosted], Long-term Brain Dopamine Dynamics: Sensor Survival during continuous recording, UCD, Science and Engineering, Chemistry [Details]
2009
Professor Robert Forster (2009) [Visiting and guest lecturers hosted], Small electrodes big impact, Dublin City University, Science and Engineering, Chemistry [Details]
2009
Professor Donal O'Shea (2009) [Visiting and guest lecturers hosted], Combining Therapuetic Treatments with Fluorescence Imaging: A Theranostic Approach, UCD, Science and Engineering, Chemistry [Details]
2009
Dr. Mary Pryce (2009) [Visiting and guest lecturers hosted], Photoactive organometallic materials, DCU, Science and Engineering, Chemistry [Details]
2009
Professor John Lowry (2009) [Visiting and guest lecturers hosted], Introduction to Electrochemistry: electrodes, cells, techniques and much more, NUIM, Science and Engineering, Chemistry [Details]
2001 Monitoring Molecules in Neuroscience, 9th International Conference on In Vivo Methods.
Lowry, J.P. and Fillenz, M. (2001) Monitoring Molecules in Neuroscience, 9th International Conference on In Vivo Methods. [Conference Organising Committee Member], University College Dublin, Ireland , 16-JUN-01 - 19-JUN-01 [Details]

Book Review

  Year Publication
1995 On the significance of brain extracellular uric acid detected with in-vivo monitoring techniques: A review.
O'Neill, R.D. and Lowry, J.P. (1995) On the significance of brain extracellular uric acid detected with in-vivo monitoring techniques: A review. Book Review [Details]

Magazine Article

  Year Publication
2009 Blue Box sensors: Ireland's newest pharmaceutical devices company.
Lowry, J.P. and Scanlan, J. (2009) Blue Box sensors: Ireland's newest pharmaceutical devices company. Magazine Article [IR Link] [Details]

Thesis

  Year Publication
2003 The development of Rapid On-Line Neurochemical Assays. Investigating the Chemical Basis of Brain Injury.
Mark C. Parkin (2003) The development of Rapid On-Line Neurochemical Assays. Investigating the Chemical Basis of Brain Injury. King’s College, London: Thesis [Details]