Dr Dania Movia

Biology

Lecturer/Assistant Professor

Callan Building
First
F1, Mezzanine
(01) 708 6850

Biography

Dr Dania Movia is an Assistant Professor in Biomedical & Health Services and a Principal Investigator at the Department of Biology at Maynooth University (Ireland). She is also an Adjunct Assistant Professor at the Discipline of Radiation Therapy of Trinity College Dublin (Ireland). 

Dr Movia graduated in Chemistry and Pharmaceutical Technologies in 2007 from the University of Trieste (Italy). She then obtained her PhD at Trinity College Dublin (Ireland) in 2012, and she was awarded a Special Purpose Certificate in Academic Practice and a Master in Arts (jure officii) by the same university in 2018 and 2023, respectively. 

Dr Movia is a member of several professional bodies and organisations, which include the Irish Lung Cancer Alliance (ILCA) and Cancer Trials Ireland. She is an active member of the scientific advisory panels of Animal-Free Research UK and FRAME-UK.

Dr Movia has authored more than 40 peer-reviewed publications. She acted as Guest Editor in Animals (MDPI) and Front. Bioeng. Biotechnol. (Frontiers) journals, and she co-edited the Cancer Cell Culture book for the Methods in Molecular Biology series, published by Springer Nature. She is currently an Associate Editor for Frontiers in Pharmacology journal. 

Research Interests

Dr Movia champions the reduction/replacement of animal testing via research and training of young scientists. Her current research work focuses on developing new, non-animal methodologies (NAMs) that can replace animal studies in lung cancer and lung toxicity research.

She has received funding in excess of €2M from several national, European and international (UK and USA) agencies including the Irish Research Council, Science Foundation Ireland, the Johns Hopkins Center for Alternatives to Animal Testing, and the European Commission. 

Research Projects

Title Role Description Start date End date Amount
Extracellular vesicles in Non-Small-Cell Lung Cancer - Finding allies among the enemies Principal Investigator 01/06/2022 31/05/2026 552000
Exploring the use of non-animal research to find new, more effective ways to monitor treatment response in people affected by lung cancer Principal Investigator 12/01/2023 30/06/2026 29143.58
Developing novel inhaled bioengineered Extracellular Vesicle RNA based advanced therapeutics, delivered by tailored aerosol delivery technology for the treatment of lung cancer (INSPIRE) Consortium partner 01/06/2022 31/05/2025 12826655
Creating a tissue-mimetic 3D model that effectively mimics angiogenesis in non-small cell lung cancer as a predictive preclinical model to test anti-angiogenic compounds for NSCLC treatment Co-applicant 01/09/2022 31/08/2025 140000

Book Chapter

Year Publication
2023 Movia, D.; Prina-Mello, A. (2023) 'A Method for Culturing 3D Tumoroids of Lung Adenocarcinoma Cells at the Air–Liquid Interface' In: Methods in Molecular Biology. [Link] [DOI]
2016 Movia, D.; Poland, C.; Tran, L.; Volkov, Y.; Prina-Mello, A. (2016) 'Multilayered nanoparticles for personalized medicine: Translation into clinical markets' In: Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications. [Link] [DOI]

Conference Publication

Year Publication
2011 Del Canto, E.; Flavin, K.; Movia, D.; Giordani, S. (2011) Materials Research Society Symposium Proceedings Oxidized single-walled carbon nanotubes: Removal of carbonaceous functionalized material by washing with solvents or base [Link] [DOI]

Peer Reviewed Journal

Year Publication
2023 Mullen, S.; Movia, D. (2023) 'The role of extracellular vesicles in non-small-cell lung cancer, the unknowns, and how new approach methodologies can support new knowledge generation in the field'. European Journal Of Pharmaceutical Sciences, 188 . [Link] [DOI]
2022 Neuhaus, W.; Reininger-Gutmann, B.; Rinner, B.; Plasenzotti, R.; Wilflingseder, D.; De Kock, J.; Vanhaecke, T.; Rogiers, V.; Jírová, D.; Kejlová, K.; Knudsen, L.E.; Nielsen, R.N.; Kleuser, B.; Kral, V.; Thöne-Reineke, C.; Hartung, T.; Pallocca, G.; Leist, M.; Hippenstiel, S.; Lang, A.; Retter, I.; Krämer, S.; Jedlicka, P.; Ameli, K.; Fritsche, E.; Tigges, J.; Buettner, M.; Bleich, A.; Baumgart, N.; Baumgart, J.; Meinhardt, M.W.; Spanagel, R.; Chourbaji, S.; Kränzlin, B.; Seeger, B.; von Köckritz-Blickwede, M.; Sánchez-Morgado, J.M.; Galligioni, V.; Ruiz-Pérez, D.; Movia, D.; Prina-Mello, A.; Ahluwalia, A.; Chiono, V.; Gutleb, A.C.; Schmit, M.; van Golen, B.; van Weereld, L.; Kienhuis, A.; van Oort, E.; van der Valk, J.; Smith, A.; Roszak, J.; Stępnik, M.; Sobańska, Z.; Olsson, I.A.S.; Franco, N.H.; Sevastre, B.; Kandarova, H.; Capdevila, S.; Johansson, J.; Cederroth, C.R.; Sandström, J.; Ragan, I.; Bubalo, N.; Spielmann, H. (2022) 'The Rise of Three Rs Centres and Platforms in Europe*'. Alternatives to Laboratory Animals, 50 . [Link] [DOI]
2022 Neuhaus, W.; Reininger-Gutmann, B.; Rinner, B.; Plasenzotti, R.; Wilflingseder, D.; De Kock, J.; Vanhaecke, T.; Rogiers, V.; Jírová, D.; Kejlová, K.; Knudsen, L.E.; Nielsen, R.N.; Kleuser, B.; Kral, V.; Thöne-Reineke, C.; Hartung, T.; Pallocca, G.; Rovida, C.; Leist, M.; Hippenstiel, S.; Lang, A.; Retter, I.; Krämer, S.; Jedlicka, P.; Ameli, K.; Fritsche, E.; Tigges, J.; Kuchovská, E.; Buettner, M.; Bleich, A.; Baumgart, N.; Baumgart, J.; Meinhardt, M.W.; Spanagel, R.; Chourbaji, S.; Kränzlin, B.; Seeger, B.; von Köckritz-Blickwede, M.; Sánchez-Morgado, J.M.; Galligioni, V.; Ruiz-Pérez, D.; Movia, D.; Prina-Mello, A.; Ahluwalia, A.; Chiono, V.; Gutleb, A.C.; Schmit, M.; van Golen, B.; van Weereld, L.; Kienhuis, A.; van Oort, E.; van der Valk, J.; Smith, A.; Roszak, J.; Stępnik, M.; Sobańska, Z.; Reszka, E.; Olsson, I.A.S.; Franco, N.H.; Sevastre, B.; Kandarova, H.; Capdevila, S.; Johansson, J.; Svensk, E.; Cederroth, C.R.; Sandström, J.; Ragan, I.; Bubalo, N.; Kurreck, J.; Spielmann, H. (2022) 'The Current Status and Work of Three Rs Centres and Platforms in Europe*'. Alternatives to Laboratory Animals, 50 . [Link] [DOI]
2022 Galligioni, V.; Movia, D.; Ruiz-Pérez, D.; Sánchez-Morgado, J.M.; Prina-Mello, A. (2022) 'The Case for Modernizing Biomedical Research in Ireland through the Creation of An Irish 3Rs Centre'. Animals, 12 . [Link] [DOI]
2021 Singh, B.; Abdelgawad, M.E.; Ali, Z.; Bailey, J.; Budyn, E.; Civita, P.; Clift, M.J.D.; Connelly, J.T.; Constant, S.; Hittinger, M.; Kandarova, H.; Kearns, V.R.; Kiuru, T.; Kostrzewski, T.; Kress, S.; Durban, V.M.; Lehr, C.M.; McMillan, H.; Metz, J.K.; Monteban, V.; Movia, D.; Neto, C.; Owen, C.; Paasonen, L.; Palmer, K.A.; Pilkington, G.J.; Pilkington, K.; Prina-Mello, A.; Roper, C.; Sheard, J.; Smith, S.; Turner, J.E.; Roy, I.; Tutty, M.A.; Velliou, E.; Wilkinson, J.M. (2021) 'Towards more predictive, physiological and animal-free in vitro models: Advances in cell and tissue culture 2020 conference proceedings'. ATLA Alternatives to Laboratory Animals, 49 . [Link] [DOI]
2020 Movia, D.; Prina-Mello, A. (2020) 'Preclinical development of orally inhaled drugs (Oids)—are animal models predictive or shall we move towards in vitro non-animal models?'. Animals, 10 . [Link] [DOI]
2020 Movia, D.; Bruni-Favier, S.; Prina-Mello, A. (2020) 'In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models—A Perspective'. Frontiers in Bioengineering and Biotechnology, 8 . [Link] [DOI]
2020 Haddada, M.B.; Movia, D.; Prina-Mello, A.; Spadavecchia, J. (2020) 'Docetaxel gold complex nanoflowers: A chemo-biological evaluation for their use as nanotherapeutics'. Colloids and Surfaces B: Biointerfaces, 194 . [Link] [DOI]
2019 Movia, D.; Bazou, D.; Prina-Mello, A. (2019) 'ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cell-fibroblast cross-talk involved in NSCLC MultiDrug Resistance'. BMC Cancer, 19 . [Link] [DOI]
2019 Moustaoui, H.; Saber, J.; Djeddi, I.; Liu, Q.; Movia, D.; Prina-Mello, A.; Spadavecchia, J.; Lamy De La Chapelle, M.; Djaker, N. (2019) 'A protein corona study by scattering correlation spectroscopy: A comparative study between spherical and urchin-shaped gold nanoparticles'. Nanoscale, 11 . [Link] [DOI]
2018 Hutchinson, D.; Müller, J.; McCarthy, J.E.; Gun’ko, Y.K.; Verma, N.K.; Bi, X.; Di Cristo, L.; Kickham, L.; Movia, D.; Prina-Mello, A.; Volkov, Y. (2018) 'Cadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: Cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease'. International Journal of COPD, 13 . [Link] [DOI]
2018 Di Cristo, L.; Maguire, C.M.; Mc Quillan, K.; Aleardi, M.; Volkov, Y.; Movia, D.; Prina-Mello, A. (2018) 'Towards the identification of an in vitro tool for assessing the biological behavior of aerosol supplied nanomaterials'. International Journal of Environmental Research and Public Health, 15 . [Link] [DOI]
2018 Prina-Mello, A.; Jain, N.; Liu, B.; Kilpatrick, J.I.; Tutty, M.A.; Bell, A.P.; Jarvis, S.P.; Volkov, Y.; Movia, D. (2018) 'Culturing substrates influence the morphological, mechanical and biochemical features of lung adenocarcinoma cells cultured in 2D or 3D'. Tissue and Cell, 50 . [Link] [DOI]
2018 Multari, C.; Miola, M.; Ferraris, S.; Movia, D.; Žužek Rožman, K.; Kostevšek, N.; Follenzi, A.; Verné, E.; Prina-Mello, A. (2018) 'Synthesis and characterization of silica-coated superparamagnetic iron oxide nanoparticles and interaction with pancreatic cancer cells'. International Journal of Applied Ceramic Technology, 15 . [Link] [DOI]
2018 Di Cristo, L.; Carthy, S.M.; Paton, K.; Movia, D.; Prina-Mello, A. (2018) 'Interplay between oxidative stress and endoplasmic reticulum stress mediated- autophagy in unfunctionalised few-layer graphene-exposed macrophages'. 2D Materials, 5 . [Link] [DOI]
2018 Movia, D.; Bazou, D.; Volkov, Y.; Prina-Mello, A. (2018) 'Multilayered Cultures of NSCLC cells grown at the Air-Liquid Interface allow the efficacy testing of inhaled anti-cancer drugs'. Scientific Reports, 8 . [Link] [DOI]
2017 Moore, C.; Movia, D.; Smith, R.J.; Hanlon, D.; Lebre, F.; Lavelle, E.C.; Byrne, H.J.; Coleman, J.N.; Volkov, Y.; McIntyre, J. (2017) 'Industrial grade 2D molybdenum disulphide (MoS2): An in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation'. 2D Materials, 4 . [Link] [DOI]
2016 Dekkers, S.; Oomen, A.G.; Bleeker, E.A.J.; Vandebriel, R.J.; Micheletti, C.; Cabellos, J.; Janer, G.; Fuentes, N.; Vázquez-Campos, S.; Borges, T.; Silva, M.J.; Prina-Mello, A.; Movia, D.; Nesslany, F.; Ribeiro, A.R.; Leite, P.E.; Groenewold, M.; Cassee, F.R.; Sips, A.J.A.M.; Dijkzeul, A.; van Teunenbroek, T.; Wijnhoven, S.W.P. (2016) 'Towards a nanospecific approach for risk assessment'. Regulatory Toxicology and Pharmacology, 80 . [Link] [DOI]
2016 Moustaoui, H.; Movia, D.; Dupont, N.; Bouchemal, N.; Casale, S.; Djaker, N.; Savarin, P.; Prina-Mello, A.; De La Chapelle, M.L.; Spadavecchia, J. (2016) 'Tunable Design of Gold(III)-Doxorubicin Complex-PEGylated Nanocarrier. the Golden Doxorubicin for Oncological Applications'. ACS Applied Materials and Interfaces, 8 . [Link] [DOI]
2016 Di Cristo, L.; Movia, D.; Bianchi, M.G.; Allegri, M.; Mohamed, B.M.; Bell, A.P.; Moore, C.; Pinelli, S.; Rasmussen, K.; Riego-Sintes, J.; Prina-Mello, A.; Bussolati, O.; Bergamaschi, E. (2016) 'Proinflammatory effects of pyrogenic and precipitated amorphous silica nanoparticles in innate immunity cells'. Toxicological Sciences, 150 . [Link] [DOI]
2016 Spadavecchia, J.; Movia, D.; Moore, C.; Maguire, C.M.; Moustaoui, H.; Casale, S.; Volkov, Y.; Prina-Mello, A. (2016) 'Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: From synthesis to proof-of-concept in vitro studies'. International journal of nanomedicine, 11 . [Link] [DOI]
2015 Rotoli, B.M.; Gatti, R.; Movia, D.; Bianchi, M.G.; Di Cristo, L.; Fenoglio, I.; Sonvico, F.; Bergamaschi, E.; Prina-Mello, A.; Bussolati, O. (2015) 'Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: A single-cell monitoring toxicity assay'. Nanotoxicology, 9 . [Link] [DOI]
2014 Schütz, C.A.; Staedler, D.; Crosbie-Staunton, K.; Movia, D.; Bernasconi, C.C.; Kenzaoui, B.H.; Prina-Mello, A.; Juillerat-Jeanneret, L. (2014) 'Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles'. International journal of nanomedicine, 9 . [Link] [DOI]
2014 Movia, D.; Gerard, V.; Maguire, C.M.; Jain, N.; Bell, A.P.; Nicolosi, V.; O'Neill, T.; Scholz, D.; Gun'ko, Y.; Volkov, Y.; Prina-Mello, A. (2014) 'A safe-by-design approach to the development of gold nanoboxes as carriers for internalization into cancer cells'. Biomaterials, 35 . [Link] [DOI]
2013 Singh, M.; Movia, D.; Mahfoud, O.K.; Volkov, Y.; Prina-Mello, A. (2013) 'Silver nanowires as prospective carriers for drug delivery in cancer treatment: An in vitro biocompatibility study on lung adenocarcinoma cells and fibroblasts'. European Journal of Nanomedicine, 5 . [Link] [DOI]
2013 Mohamed, B.M.; Movia, D.; Knyazev, A.; Langevin, D.; Davies, A.M.; Prina-Mello, A.; Volkov, Y. (2013) 'Citrullination as early-stage indicator of cell response to Single-Walled Carbon Nanotubes'. Scientific Reports, 3 . [Link] [DOI]
2012 Schinwald, A.; Murphy, F.A.; Prina-Mello, A.; Poland, C.A.; Byrne, F.; Movia, D.; Glass, J.R.; Dickerson, J.C.; Schultz, D.A.; Jeffree, C.E.; Macnee, W.; Donaldson, K. (2012) 'The threshold length for fiber-induced acute pleural inflammation: Shedding light on the early events in asbestos-induced mesothelioma'. Toxicological Sciences, 128 . [Link] [DOI]
2012 Canto, E.D.; Natali, M.; Movia, D.; Giordani, S. (2012) 'Photo-controlled release of zinc metal ions by spiropyran receptors anchored to single-walled carbon nanotubes'. Physical Chemistry Chemical Physics, 14 . [Link] [DOI]
2011 Del Canto, E.; Flavin, K.; Movia, D.; Navio, C.; Bittencourt, C.; Giordani, S. (2011) 'Critical investigation of defect site functionalization on single-walled carbon nanotubes'. Chemistry of Materials, 23 . [Link] [DOI]
2011 Movia, D.; Prina-Mello, A.; Bazou, D.; Volkov, Y.; Giordani, S. (2011) 'Screening the cytotoxicity of single-walled carbon nanotubes using novel 3D tissue-mimetic models'. ACS Nano, 5 . [Link] [DOI]
2011 Leblanc, R.M.; Thakur, G.; Micic, M.; Yang, Y.; Li, W.; Movia, D.; Giordani, S.; Zhang, H. (2011) 'Conjugated quantum dots inhibit the amyloid β(1-42) fibrillation process'. International Journal of Alzheimer's Disease, . [Link] [DOI]
2010 Movia, D.; Prina-Mello, A.; Volkov, Y.; Giordani, S. (2010) 'Determination of spiropyran cytotoxicity by high content screening and analysis for safe application in bionanosensing'. Chemical Research in Toxicology, 23 . [Link] [DOI]
2010 Movia, D.; Del Canto, E.; Giordani, S. (2010) 'Purified and oxidized single-walled carbon nanotubes as robust near-IR fluorescent probes for molecular imaging'. Journal of Physical Chemistry C, 114 . [Link] [DOI]
2009 Movia, D.; Del Canto, E.; Giordani, S. (2009) 'Spectroscopy of single-walled carbon nanotubes in aqueous surfactant dispersion'. Physica Status Solidi (B) Basic Research, 246 . [Link] [DOI]

Other Publication

Year Publication
2023 Movia, D.; Prina-Mello, A. (2023) Preface. [Link]
2022 Tutty, M.A.; Movia, D.; Prina-Mello, A. (2022) Three-dimensional (3D) liver cell models - a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of nanobiomaterials. [Link] [DOI]
2021 Prina-Mello, A.; Bonacina, L.; Staedler, D.; Movia, D. (2021) Editorial: Use of 3D Models in Drug Development and Precision Medicine - Advances and Outlook. [Link] [DOI]
2016 Bregoli, L.; Movia, D.; Gavigan-Imedio, J.D.; Lysaght, J.; Reynolds, J.; Prina-Mello, A. (2016) Nanomedicine applied to translational oncology: A future perspective on cancer treatment. [Link] [DOI]
2014 Mahfoud, O.K.; Rakovich, T.Y.; Prina-Mello, A.; Movia, D.; Alves, F.; Volkov, Y. (2014) Detection of ErbB2: Nanotechnological solutions for clinical diagnostics. [Link] [DOI]
Certain data included herein are derived from the © Web of Science (2023) of Clarivate. All rights reserved.

Professional Associations

Description Function From / To
ILCA (Irish Lung Cancer Alliance) Member -
Cancer Trials Ireland Member -
EACR (European Association for Cancer Research) Member -

Honors and Awards

Date Title Awarding Body
17/06/2023 Master in Arts (jure officii) Trinity College Dublin

Employment

Employer Position From / To
Trinity College Dublin Research assistant -
Trinity College Dublin Research fellow -
Trinity College Dublin Senior research fellow -
Trinity College Dublin Post-doctoral research fellow -
Trinity College Dublin Assistant professor -

Education

Start date Institution Qualification Subject
Trinity College Dublin PhD in Chemistry Chemistry
Università degli Studi di Trieste MSc in Chemistry and Pharmaceutical Technologies Pharmacy
Trinity College Dublin Special Purpose Certificate in Academic Practice Education

Editorial / Academic Reviews

Amount Role From / To
Frontiers in Bioengineering and Biotechnology Guest Editor -
Frontiers in Pharmacology Reviewing Editor -
Frontiers in Pharmacology Associate Editor -
Animals Guest Editor -
Cancer Cell Culture Methods and Protocols (book) Editor -