Dr Stephen Barrett

Chemistry, Human Health Institute

Assistant Lecturer

Education House
3.1.3
(01) 708 3954

Biography

2024 - Assistant Lecturer, Dept. of Chemistry, Maynooth University.

2022 - 2024 - Irish Research Council Post Doctoral research fellow, Dept. of Chemistry, Royal College Of Surgeons Ireland.

2021 - 2022 - Assistant Lecturer, Dept. of Chemistry Maynooth University

2021 - PhD. in Chemistry, Maynooth University, Ireland

2020 - Visiting Lecturer, Dept. of Chemistry, CCZU, Changzhou University, China


Research Interests

The Barrett research groups primary interest is in metal based anti - cancer therapeutics and metal based complexes which display anti - microbial activities. Our research falls under the large umbrella of Bio-Inorganic Chemistry and  is at the interface of Chemistry & Biology.

We are specifically interested in metal based complexes as targeted anti - cancer and anti - microbial therapeutics. 

In particular:


1) Photoactive Pt(IV) complexes as potential chemotherapy drugs.

2) Targeted Cu(II) small molecule drugs which interact with DNA & RNA.

3) Targeted Cu(II) complexes with anti microbial and anti- cancer properties . 

4) Pt(II) anti - cancer complexes which are activated in the cell via bioorthogonal pathways.


Peer Reviewed Journal

Year Publication
2023 Barrett, S.; De Franco, M.; Donati, C.; Marzano, C.; Gandin, V.; Montagner, D. (2023) 'Novel Biotinylated Cu(II)-Phenanthroline Complexes: 2D and 3D Cytotoxic Activity and Mechanistic Insight'. Molecules (Basel, Switzerland), 28 . [Link] [DOI]
2019 Barrett, S; De Franco, M; Kellett, A; Dempsey, E; Marzano, C; Erxleben, A; Gandin, V; Montagner, D (2019) 'Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes'. Journal of Biological Inorganic Chemistry, . [DOI] [Full-Text]
2018 Barrett S.; Delaney S.; Kavanagh K.; Montagner D. (2018) 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'. Inorganica Chimica Acta, 479 :261-265. [DOI] [Full-Text]

Book Chapter

Year Publication
2022 Frances Heaney, Denise Rooney, Orla Fenelon, Tobias Krämer, Eithne Dempsey, Stephen Barrett, Caytlin Boylan, Kyle Doherty, Luke Marchetti, Joseph Curran, Lisa O’Regan, Trinidad Velasco-Torrijos (2022) 'A Whole Team Approach to Integration of Student Feedback into Continuous Assessment Activities for First-Year Students Transitioning to University Chemistry Education during the COVID-19 Pandemic' In: University Chemistry Teaching in the 21. Century. Poland : Pedagoška fakulteta Univerze v Ljubljani. https://doi.org/10.26529/9789612532970/ch4
Certain data included herein are derived from the © Web of Science (2024) of Clarivate. All rights reserved.

Professional Associations

Description Function From / To
IBICS Irish Biological Inorganic Chemistry Society Member -
Royal Society of Chemistry Member -

Honors and Awards

Date Title Awarding Body
01/09/2022 Irish Research Council post Doctoral Fellowship Irish Research Council GOIPD/2022/160

Editorial / Academic Reviews

Amount Role From / To
Frontiers In Chemistry Reviewer -
Dalton Transactions Reviewer -