Prof Kevin Kavanagh

Biology, Human Health Institute

Professor
Biological & Biomedical Science Programme Coordinator

Callan
2.39
(01) 708 3859

Biography

Prof. Kevin Kavanagh graduated with a BSc (Joint Honours) degree in Biology and Chemistry and undertook a PhD in Microbiology. He undertook postdoctoral research in projects in Maynooth and University of Kuwait, and the National Cell and Tissue Culture Centre in Dublin City University. He was appointed as a Lecturer in 1995 and promoted to Senior Lecturer in 2002. Currently he is Director and CSO of Beemune Ltd - a NUI Maynooth spin-out company. He was appointed as a visiting Lecturer in Medical Mycology at Queen's University Belfast in 2009

Book Chapters

  Year Publication
2011 'Fungal Fermentations Systems and Products'
Kavanagh, K (2011) 'Fungal Fermentations Systems and Products' In: FUNGI: BIOLOGY AND APPLICATIONS, 2ND EDITION. OXFORD: BLACKWELL SCIENCE PUBL. [Details]
2011 'Fungal Fermentations Systems and Products'
Kavanagh K. (2011) 'Fungal Fermentations Systems and Products' In: Fungi: Biology and Applications. [DOI] [Details]
2007 'Insects as models for studying the virulence of fungal pathogens of humans'
Renwick J.;Kavanagh K. (2007) 'Insects as models for studying the virulence of fungal pathogens of humans' In: New Insights in Medical Mycology. [DOI] [Details]
2007 'Extraction and Detection of DNA and RNA from Yeast'
Geraghty P.;Kavanagh K. (2007) 'Extraction and Detection of DNA and RNA from Yeast' In: Medical Mycology: Cellular and Molecular Techniques. [DOI] [Details]
2007 'Fungi'
Kavanagh K.;Sullivan D. (2007) 'Fungi' In: Hugo and Russell's Pharmaceutical Microbiology: Seventh Edition. [DOI] [Details]
2006 'Extraction and Detection of DNA and RNA from Yeast'
Geraghty, P & Kavanagh, K. (2006) 'Extraction and Detection of DNA and RNA from Yeast' In: Medical Mycology: Cellular and Molecular Techniques. . Chichester, UK: Wiley & Co. Ltd. [Details]
2005 'Fungal Fermentation Systems and Products'
Kavanagh K. (2005) 'Fungal Fermentation Systems and Products' In: Fungi: Biology and Applications. [DOI] [Details]
2005 'Fungal Fermentation: Technology and Products'
Kavanagh, K. (2005) 'Fungal Fermentation: Technology and Products' In: Fungi: Biology and Applications. Chichester, UK: Wiley & Co. Ltd. [Details]
2004 'Biology of Microorganisms: Fungi'
Kavanagh, K. & Sullivan, D. (2004) 'Biology of Microorganisms: Fungi' In: Pharmaceutical Microbiology. Blackwells. [Details]
2003 'Yeasts and Molds'
Kavanagh K & Sullivan D (2003) 'Yeasts and Molds' In: Pharmaceutical Microbiology. [Details]
2002 'Protoplasts'
Kavanagh, K. & Whittaker P.A. (2002) 'Protoplasts' In: Encyclopedia of Molecular Biology. New York: Wiley and Sons. [Details]
2002 'Protoplast Fusion'
Kavanagh K., & Whittaker P. (2002) 'Protoplast Fusion' In: Encyclopedia of Molecular Biology. New York: Wiley and Sons. [Details]
1994 'Development of a Hybridoma Cloning Medium'
Weedle,R. K. Carroll, K. Kavanagh, R O'Kennedy, & M. Clynes. (1994) 'Development of a Hybridoma Cloning Medium' In: Animal Cell Technology: Products of Today, Prospects for Tomorrow. Oxford: Butterworth-Heinemann. [Details]

Books

  Year Publication
2011 Fungi: Biology and Applications.
Kavanagh K. (2011) Fungi: Biology and Applications. [DOI] [Details]
2011 Fungi: Biology and Applications - Second Edition.
Dr Kevin A Kavanagh (2011) Fungi: Biology and Applications - Second Edition. : Wiley & Co., Ltd. [Details]
2007 Medical Mycology: Cellular and Molecular Techniques.
Kavanagh K. (2007) Medical Mycology: Cellular and Molecular Techniques. [DOI] [Details]
2007 New insights in medical mycology.
Kavanagh K. (2007) New insights in medical mycology. [DOI] [Details]
2005 Fungi: Biology and Applications.
Kavanagh K. (2005) Fungi: Biology and Applications. [DOI] [Details]
2007 New Insights in Medical Mycology.
Kavanagh, K. (2007) New Insights in Medical Mycology. : Springer. [Details]
2006 Medical Mycology: Cellular and Molecular Techniques. .
Kavanagh, K. (2006) Medical Mycology: Cellular and Molecular Techniques. . : Wiley & Co. Ltd. [Details]
2001 A Teachers Guide to Studying the Virulence factors of the Yeast Candida albicans.
Kavanagh K (2001) A Teachers Guide to Studying the Virulence factors of the Yeast Candida albicans. : Society for General Microbiology. [Details]

Peer Reviewed Journals

  Year Publication
2018 'Innate humoral immune defences in mammals and insects: The same, with differences ?'
Sheehan G.;Garvey A.;Croke M.;Kavanagh K. (2018) 'Innate humoral immune defences in mammals and insects: The same, with differences ?'. Virulence, 9 (1):1625-1639 [DOI] [Details]
2018 'Inhibition of adherence of the yeast Candida albicans to buccal epithelial cells by synthetic aromatic glycoconjugates'
Martin H;Govern MM;Abbey L;Gilroy A;Mullins S;Howell S;Kavanagh K;Velasco-Torrijos T; (2018) 'Inhibition of adherence of the yeast Candida albicans to buccal epithelial cells by synthetic aromatic glycoconjugates'. European Journal of Medicinal Chemistry, 160 [DOI] [Details]
2018 'Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor'
Surlis C;Carolan JC;Coffey M;Kavanagh K; (2018) 'Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor'. Journal of Insect Physiology, [DOI] [Details]
2018 'Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and109Ag NMR studies'
O'Beirne C.;Althani H.;Dada O.;Cassidy J.;Kavanagh K.;Müller-Bunz H.;Ortin Y.;Zhu X.;Tacke M. (2018) 'Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and109Ag NMR studies'. Polyhedron, 149 :95-103 [DOI] [Details]
2018 'Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections'
Aneja B.;Azam M.;Alam S.;Perwez A.;Maguire R.;Yadava U.;Kavanagh K.;Daniliuc C.;Rizvi M.;Haq Q.;Abid M. (2018) 'Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections'. Acs Omega, 3 (6):6912-6930 [DOI] [IR Link] [Details]
2018 'Characterisation of the cellular and proteomic response of Galleria mellonella larvae to the development of invasive aspergillosis'
Sheehan G.;Clarke G.;Kavanagh K. (2018) 'Characterisation of the cellular and proteomic response of Galleria mellonella larvae to the development of invasive aspergillosis'. BMC Microbiology, 18 (1) [DOI] [IR Link] [Details]
2018 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'
Barrett S.;Delaney S.;Kavanagh K.;Montagner D. (2018) 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'. Inorganica Chimica Acta, 479 :261-265 [DOI] [Details]
2018 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'
Stephen Barrett , Stephen Delaney, Kevin Kavanagh, Diego Montagner* (2018) 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'. Inorganica Chimica Acta, 479 :261-265 [DOI] [Details]
2018 'Unprecedented in vitro antitubercular activitiy of manganese(II) complexes containing 1,10-phenanthroline and dicarboxylate ligands: Increased activity, superior selectivity, and lower toxicity in comparison to their copper(II) analogs'
McCarron P.;McCann M.;Devereux M.;Kavanagh K.;Skerry C.;Karakousis P.;Aor A.;Mello T.;Santos A.;Campos D.;Pavan F. (2018) 'Unprecedented in vitro antitubercular activitiy of manganese(II) complexes containing 1,10-phenanthroline and dicarboxylate ligands: Increased activity, superior selectivity, and lower toxicity in comparison to their copper(II) analogs'. Frontiers in Microbiology, 9 (JUL) [DOI] [IR Link] [Details]
2018 'Analysis of the effect of temperature on protein abundance in Demodex-associated Bacillus oleronius'
Maher A.;Staunton K.;Kavanagh K. (2018) 'Analysis of the effect of temperature on protein abundance in Demodex-associated Bacillus oleronius'. Pathogens and Disease, 76 (4) [DOI] [Details]
2018 'In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes'
Rochford G.;Molphy Z.;Browne N.;Surlis C.;Devereux M.;McCann M.;Kellett A.;Howe O.;Kavanagh K. (2018) 'In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes'. Journal of Inorganic Biochemistry, 186 :135-146 [DOI] [Details]
2018 'The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis'
Namara LM;Griffin CT;Fitzpatrick D;Kavanagh K;Carolan JC; (2018) 'The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis'. Insect Biochemistry and Molecular Biology, [DOI] [IR Link] [Details]
2018 'Efficacy of entomopathogenic fungi against large pine weevil, Hylobius abietis, and their additive effects when combined with entomopathogenic nematodes'
Mc Namara L.;Kapranas A.;Williams C.;O’Tuama P.;Kavanagh K.;Griffin C. (2018) 'Efficacy of entomopathogenic fungi against large pine weevil, Hylobius abietis, and their additive effects when combined with entomopathogenic nematodes'. Journal of Pest Science, :1-13 [DOI] [Details]
2018 'The human cathelicidin antimicrobial peptide LL-37 promotes the growth of the pulmonary pathogen Aspergillus fumigatus'
Sheehan G.;Bergsson G.;McElvaney N.;Reeves E.;Kavanagh K. (2018) 'The human cathelicidin antimicrobial peptide LL-37 promotes the growth of the pulmonary pathogen Aspergillus fumigatus'. Infection and Immunity, 86 (7) [DOI] [Details]
2017 'Steroid-Au(I)-NHC Complexes: Synthesis and Antibacterial Activity'
Velle', Maguire, Kavanagh, Sanz Miguel, Montagner* (2017) 'Steroid-Au(I)-NHC Complexes: Synthesis and Antibacterial Activity'. ChemMedChem, 12 :841-844 [DOI] [IR Link] [Details]
2017 'Glycosylated metal chelators as anti-parasitic agents with tunable selectivity'
Reddy A;Sangenito LS;Guedes AA;Branquinha MH;Kavanagh K;McGinley J;Dos Santos ALS;Velasco-Torrijos T; (2017) 'Glycosylated metal chelators as anti-parasitic agents with tunable selectivity'. Dalton Transactions, 46 (16) [DOI] [IR Link] [Details]
2017 'Caffeine administration alters the behaviour and development of Galleria mellonella larvae'
Maguire R.;Kunc M.;Hyrsl P.;Kavanagh K. (2017) 'Caffeine administration alters the behaviour and development of Galleria mellonella larvae'. Neurotoxicology and Teratology, 64 :37-44 [DOI] [IR Link] [Details]
2017 'Analysis of the acute response of Galleria mellonella larvae to potassium nitrate'
Maguire R.;Kunc M.;Hyrsl P.;Kavanagh K. (2017) 'Analysis of the acute response of Galleria mellonella larvae to potassium nitrate'. Comparative Biochemistry and Physiology, Part C, 195 :44-51 [DOI] [IR Link] [Details]
2017 'Steroid–AuI–NHC Complexes: Synthesis and Antibacterial Activity'
Vellé A.;Maguire R.;Kavanagh K.;Sanz Miguel P.;Montagner D. (2017) 'Steroid–AuI–NHC Complexes: Synthesis and Antibacterial Activity'. ChemMedChem, 12 (11):841-844 [DOI] [IR Link] [Details]
2017 'Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans'
Sheehan G.;Kavanagh K. (2017) 'Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans'. Virulence, :1-10 [DOI] [IR Link] [Details]
2017 'The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella'
Mc Namara L;Carolan JC;Griffin CT;Fitzpatrick D;Kavanagh K; (2017) 'The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella'. Journal of Insect Physiology, 100 [DOI] [IR Link] [Details]
2017 'The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella'
Mc Namara, L;Carolan, JC;Griffin, CT;Fitzpatrick, D;Kavanagh, K (2017) 'The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella'. Journal of Insect Physiology, 100 :82-92 [DOI] [IR Link] [Details]
2017 'Detection of Trichoderma aggressivum in bulk phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'
O’Brien M.;Kavanagh K.;Grogan H. (2017) 'Detection of Trichoderma aggressivum in bulk phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'. European Journal of Plant Pathology, 147 (1):199-209 [DOI] [IR Link] [Details]
2016 'Synthesis of Silver(I) Complexes Of Coumarin-Based Ligands And Their Phenanthroline Adducts: Structural Characterisation and Antimicrobial Activity'
Mujahid M., Trendafilova N., Foltyn-Kia A., Rosair G., Kavanagh K., Walsh M., McClean S., Creaven. BS, Georgieva I. (2016) 'Synthesis of Silver(I) Complexes Of Coumarin-Based Ligands And Their Phenanthroline Adducts: Structural Characterisation and Antimicrobial Activity'. Journal of Inorganic Biochemistry, 163 :53-57 [IR Link] [Details]
2016 'Evaluation of Galleria mellonella larvae for studying the virulence of Streptococcus suis'
Velikova N;Kavanagh K;Wells JM; (2016) 'Evaluation of Galleria mellonella larvae for studying the virulence of Streptococcus suis'. BMC Microbiology, 16 (1) [DOI] [IR Link] [Details]
2016 'Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents'
Maguire R, Duggan O, Kavanagh K (2016) 'Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents'. Cell Biology and Toxicology, 32 :209-216 [IR Link] [Details]
2016 'Effect of novel triazole-amino acid hybrids on growth and virulence of Candida species: In vitro and in vivo studies'
Aneja B, Irfan M, Kapil C, Jairajpuri MA, Maguire R, Kavanagh K, Manzoor N, Azam A, Abid M. (2016) 'Effect of novel triazole-amino acid hybrids on growth and virulence of Candida species: In vitro and in vivo studies'. Organic and Biomolecular Chemistry, 14 :10599-10619 [IR Link] [Details]
2016 'Detection of Trichoderma aggressivum in bulk Phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'
O’Brien M, Kavanagh K, Grogan H (2016) 'Detection of Trichoderma aggressivum in bulk Phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'. European Journal of Plant Pathology, 147 :199-209 [IR Link] [Details]
2016 'Novel silver(I) complexes of coumarin oxyacetate ligands and their phenanthroline adducts: Biological activity, structural and spectroscopic characterisation'
Mujahid M.;Trendafilova N.;Arfa-Kia A.;Rosair G.;Kavanagh K.;Devereux M.;Walsh M.;McClean S.;Creaven B.;Georgieva I. (2016) 'Novel silver(I) complexes of coumarin oxyacetate ligands and their phenanthroline adducts: Biological activity, structural and spectroscopic characterisation'. Journal of Inorganic Biochemistry, 163 :53-67 [DOI] [IR Link] [Details]
2016 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'
Dolan N, Gavin DP, Eshwika A, Kavanagh K, McGinley J and Stephens JC (2016) 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'. Bioorganic and Medicinal Chemistry, 26 :630-635 [IR Link] [Details]
2016 'Proteomic analysis of Bayvarol® resistance mechanisms in the honey bee parasite Varroa destructor'
Surlis C.;Carolan J.;Coffey M.;Kavanagh K. (2016) 'Proteomic analysis of Bayvarol® resistance mechanisms in the honey bee parasite Varroa destructor'. Journal of Apicultural Research, :1-16 [DOI] [IR Link] [Details]
2016 'Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents'
Maguire R.;Duggan O.;Kavanagh K. (2016) 'Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents'. Cell Biology and Toxicology, 32 (3):209-216 [DOI] [IR Link] [Details]
2016 'Effect of novel triazole-amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies'
Aneja B.;Irfan M.;Kapil C.;Jairajpuri M.;Maguire R.;Kavanagh K.;Rizvi M.;Manzoor N.;Azam A.;Abid M. (2016) 'Effect of novel triazole-amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies'. Organic and Biomolecular Chemistry, 14 (45):10599-10619 [DOI] [IR Link] [Details]
2016 'Activation of Neutrophils via IP3Pathway Following Exposure to Demodex-Associated Bacterial Proteins'
McMahon F.;Banville N.;Bergin D.;Smedman C.;Paulie S.;Reeves E.;Kavanagh K. (2016) 'Activation of Neutrophils via IP3Pathway Following Exposure to Demodex-Associated Bacterial Proteins'. Journal of Inflammation, 39 (1):425-433 [DOI] [IR Link] [Details]
2016 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'
Dolan, N;Gavin, DP;Eshwika, A;Kavanagh, K;McGinley, J;Stephens, JC (2016) 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'. Bioorganic and Medicinal Chemistry Letters, 26 :630-635 [DOI] [IR Link] [Details]
2015 'Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection'
Browne, N;Surlis, C;Maher, A;Gallagher, C;Carolan, JC;Clynes, M;Kavanagh, K (2015) 'Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection'. Virulence, 6 :458-465 [DOI] [IR Link] [Details]
2015 'Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance'
Maurer, E;Browne, N;Surlis, C;Jukic, E;Moser, P;Kavanagh, K;Lass-Florl, C;Binder, U (2015) 'Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance'. Virulence, 6 :603-610 [DOI] [IR Link] [Details]
2014 'Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients'
Jarmuda, S;McMahon, F;Zaba, R;O'Reilly, N;Jakubowicz, O;Holland, A;Szkaradkiewicz, A;Kavanagh, K (2014) 'Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients'. Journal of Medical Microbiology, 63 :258-262 [DOI] [IR Link] [Details]
2014 'Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives'
Dolan, N;McGinley, J;Stephens, JC;Kavanagh, K;Hurley, D;Maher, NJ (2014) 'Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives'. Inorganica Chimica Acta, 409 :276-284 [DOI] [IR Link] [Details]
2014 'Isolation and characterisation of silver(I) complexes of substituted coumarin-4-carboxylates which are effective against Pseudomonas aeruginosa biofilms'
Sullivan, M;Kia, AFA;Long, M;Walsh, M;Kavanagh, K;McClean, S;Creaven, BS (2014) 'Isolation and characterisation of silver(I) complexes of substituted coumarin-4-carboxylates which are effective against Pseudomonas aeruginosa biofilms'. Polyhedron, 67 :549-559 [DOI] [IR Link] [Details]
2014 'Proteomic response of Trichoderma aggressivum f. europaeum to Agaricus bisporus tissue and mushroom compost'
O'Brien, M;Grogan, H;Kavanagh, K (2014) 'Proteomic response of Trichoderma aggressivum f. europaeum to Agaricus bisporus tissue and mushroom compost'. Fungal Biology, 118 :785-791 [DOI] [IR Link] [Details]
2014 'Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response'
McMahon, FW;Gallagher, C;O'Reilly, N;Clynes, M;O'Sullivan, F;Kavanagh, K (2014) 'Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response'. Investigative Ophthalmology & Visual Science, 55 [DOI] [IR Link] [Details]
2014 'Thermal and physical stresses induce a short-term immune priming effect in Galleria mellonella larvae'
Browne, N;Surlis, C;Kavanagh, K (2014) 'Thermal and physical stresses induce a short-term immune priming effect in Galleria mellonella larvae'. Journal of Insect Physiology, 63 :21-26 [DOI] [IR Link] [Details]
2014 'Assessment of in vivo antimicrobial activity of the carbene silver(I) acetate derivative SBC3 using Galleria mellonella larvae'
Browne, N;Hackenberg, F;Streciwilk, W;Tacke, M;Kavanagh, K (2014) 'Assessment of in vivo antimicrobial activity of the carbene silver(I) acetate derivative SBC3 using Galleria mellonella larvae'. BioMetals, 27 :745-752 [DOI] [IR Link] [Details]
2013 'Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles'
McCann, M;Curran, R;Ben-Shoshan, M;McKee, V;Devereux, M;Kavanagh, K;Kellett, A (2013) 'Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles'. Polyhedron, 56 :180-188 [DOI] [IR Link] [Details]
2013 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1B gamma deletion in Aspergillus fumigatus'
O'Keeffe, G;Jochl, C;Kavanagh, K;Doyle, S (2013) 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1B gamma deletion in Aspergillus fumigatus'. Protein Science, 22 :1612-1622 [DOI] [IR Link] [Details]
2013 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'
Eshwika, A;Kelly, J;Fallon, JP;Kavanagh, K (2013) 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'. Medical Mycology, 51 :121-127 [DOI] [IR Link] [Details]
2013 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus'
O'Keeffe G.;Jöchl C.;Kavanagh K.;Doyle S. (2013) 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus'. Protein Science, 22 (11):1612-1622 [DOI] [IR Link] [Details]
2013 'Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I)'
Smith, A;McCann, M;Kavanagh, K (2013) 'Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I)'. Toxicology in Vitro, 27 :1644-1648 [DOI] [IR Link] [Details]
2013 'Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities'
McGinley, J;McCann, M;Ni, KJ;Tallon, T;Kavanagh, K;Devereux, M;Ma, XM;McKee, V (2013) 'Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities'. Polyhedron, 55 :169-178 [DOI] [IR Link] [Details]
2013 'A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction'
McCann, M;McGinley, J;Ni, K;O'Connor, M;Kavanagh, K;Mckee, V;Colleran, J;Devereux, M;Gathergood, N;Barron, N;Prisecaru, A;Kellett, A (2013) 'A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction'. Chemical Communications, 49 :2341-2343 [DOI] [IR Link] [Details]
2013 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells (Retraction of vol 250, pg 128, 2007)'
Thati, B;Noble, A;Creaven, BS;Walsh, M;McCann, M;Kavanagh, K;Devereux, M;Egan, DA (2013) 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells (Retraction of vol 250, pg 128, 2007)'. Cancer Letters, 337 :146-146 [DOI] [Details]
2012 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'
Gallagher, L;Owens, RA;Dolan, SK;O'Keeffe, G;Schrettl, M;Kavanagh, K;Jones, GW;Doyle, S (2012) 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'. Eukaryotic Cell, 11 :1226-1238 [DOI] [IR Link] [Details]
2012 'Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea'
O'Reilly, N;Menezes, N;Kavanagh, K (2012) 'Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea'. British Journal of Dermatology, 167 :1032-1036 [DOI] [Details]
2012 'Gliotoxin effects on fungal growth: Mechanisms and exploitation'
Carberry, S;Molloy, E;Hammel, S;O'Keeffe, G;Jones, GW;Kavanagh, K;Doyle, S (2012) 'Gliotoxin effects on fungal growth: Mechanisms and exploitation'. Fungal Genetics and Biology, 49 :302-312 [DOI] [IR Link] [Details]
2012 'Demodex-associated bacterial proteins induce neutrophil activation'
O'Reilly, N;Bergin, D;Reeves, EP;McElvaney, NG;Kavanagh, K (2012) 'Demodex-associated bacterial proteins induce neutrophil activation'. British Journal of Dermatology, 166 :753-760 [DOI] [IR Link] [Details]
2012 'Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection'
Banville, N;Browne, N;Kavanagh, K (2012) 'Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection'. Virulence, 3 :497-503 [DOI] [IR Link] [Details]
2012 'In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes'
McCann, M;Santos, ALS;da Silva, BA;Romanos, MTV;Pyrrho, AS;Devereux, M;Kavanagh, K;Fichtner, I;Kellett, A (2012) 'In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes'. Toxicology Research, 1 :47-54 [DOI] [IR Link] [Details]
2012 'Deciphering the antimicrobial activity of phenanthroline chelators'
McCann M.;Kellett A.;Kavanagh K.;Devereux M.;Santos A. (2012) 'Deciphering the antimicrobial activity of phenanthroline chelators'. Current Medicinal Chemistry, 19 (17):2703-2714 [Details]
2012 'Exposure of Staphylococcus aureus to silver(I) induces a short term protective response'
Smith, A;Rowan, R;McCann, M;Kavanagh, K (2012) 'Exposure of Staphylococcus aureus to silver(I) induces a short term protective response'. BioMetals, 25 :611-616 [DOI] [IR Link] [Details]
2012 'The Effect of Aspergillus fumigatus Infection on Vitamin D Receptor Expression in Cystic Fibrosis'
Coughlan, CA;Chotirmall, SH;Renwick, J;Hassan, T;Low, TB;Bergsson, G;Eshwika, A;Bennett, K;Dunne, K;Greene, CM;Gunaratnam, C;Kavanagh, K;Logan, PM;Murphy, P;Reeves, EP;McElvaney, NG (2012) 'The Effect of Aspergillus fumigatus Infection on Vitamin D Receptor Expression in Cystic Fibrosis'. American Journal of Respiratory and Critical Care Medicine, 186 :999-1007 [DOI] [IR Link] [Details]
2012 'Nonribosomal Peptide Synthetase Genes pesL and pes1 Are Essential for Fumigaclavine C Production in Aspergillus fumigatus'
O'Hanlon, KA;Gallagher, L;Schrettl, M;Jochl, C;Kavanagh, K;Larsen, TO;Doyle, S (2012) 'Nonribosomal Peptide Synthetase Genes pesL and pes1 Are Essential for Fumigaclavine C Production in Aspergillus fumigatus'. Applied And Environmental Microbiology, 78 :3166-3176 [DOI] [IR Link] [Details]
2012 'Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea'
O'Reilly, N;Gallagher, C;Katikireddy, KR;Clynes, M;O'Sullivan, F;Kavanagh, K (2012) 'Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea'. Investigative Ophthalmology & Visual Science, 53 :3250-3259 [DOI] [IR Link] [Details]
2012 'Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity'
McCann, M;Curran, R;Ben-Shoshan, M;McKee, V;Tahir, AA;Devereux, M;Kavanagh, K;Creaven, BS;Kellett, A (2012) 'Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity'. Dalton Transactions, 41 :6516-6527 [DOI] [IR Link] [Details]
2011 'Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry'
Davis, C;Gordon, N;Murphy, S;Singh, I;Kavanagh, K;Carberry, S;Doyle, S (2011) 'Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry'. Analytical and Bioanalytical Chemistry, 401 :2519-2529 [DOI] [IR Link] [Details]
2011 'Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response'
Kelly, J;Kavanagh, K (2011) 'Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response'. Journal of Medical Microbiology, 60 :189-196 [DOI] [IR Link] [Details]
2011 'Water-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug development'
Kellett, A;O'Connor, M;McCann, M;Howe, O;Casey, A;McCarron, P;Kavanagh, K;McNamara, M;Kennedy, S;May, DD;Skell, PS;O'Shea, D;Devereux, M (2011) 'Water-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug development'. MedChemComm, 2 :579-584 [DOI] [IR Link] [Details]
2011 'Candida Urinary Tract Infection: Pathogenesis'
Fisher, JF;Kavanagh, K;Sobel, JD;Kauffman, CA;Newman, CA (2011) 'Candida Urinary Tract Infection: Pathogenesis'. Clinical Infectious Diseases, 52 :437-451 [DOI] [IR Link] [Details]
2011 'The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus'
Davis, C;Carberry, S;Schrettl, M;Singh, I;Stephens, JC;Barry, SM;Kavanagh, K;Challis, GL;Brougham, D;Doyle, S (2011) 'The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 18 :542-552 [DOI] [IR Link] [Details]
2011 'The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes'
Fallon, JP;Reeves, EP;Kavanagh, K (2011) 'The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes'. Microbiology - Society for General Microbiology, 157 :1481-1488 [DOI] [IR Link] [Details]
2011 'Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity'
Griffith, DM;Duff, B;Suponitsky, KY;Kavanagh, K;Morgan, MP;Egan, D;Marmion, CJ (2011) 'Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity'. Journal of Inorganic Biochemistry, 105 :793-799 [DOI] [IR Link] [Details]
2011 'Disruption of haemocyte function by exposure to cytochalasin b or nocodazole increases the susceptibility of Galleria mellonella larvae to infection'
Banville, N;Fallon, J;McLoughlin, K;Kavanagh, K (2011) 'Disruption of haemocyte function by exposure to cytochalasin b or nocodazole increases the susceptibility of Galleria mellonella larvae to infection'. Microbes and Infection, 13 :1191-1198 [DOI] [Details]
2011 'Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus'
O'Hanlon, KA;Cairns, T;Stack, D;Schrettl, M;Bignell, EM;Kavanagh, K;Miggin, SM;O'Keeffe, G;Larsen, TO;Doyle, S (2011) 'Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus'. Infection and Immunity, 79 :3978-3992 [DOI] [IR Link] [Details]
2011 'Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responses'
Fallon, JP;Troy, N;Kavanagh, K (2011) 'Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responses'. Virulence, 2 :413-421 [DOI] [IR Link] [Details]
2011 'Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells'
Costello, A;Herbert, G;Fabunmi, L;Schaffer, K;Kavanagh, KA;Caraher, EM;Callaghan, M;McClean, S (2011) 'Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells'. Journal of Medical Microbiology, 60 :289-299 [DOI] [IR Link] [Details]
2010 'Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases'
Creaven, BS;Duff, B;Egan, DA;Kavanagh, K;Rosair, G;Thangella, VR;Walsh, M (2010) 'Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases'. Inorganica Chimica Acta, 363 :4048-4058 [DOI] [IR Link] [Details]
2010 'Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin'
Kelly, J;Kavanagh, K (2010) 'Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin'. Medical Mycology, 48 :598-605 [DOI] [IR Link] [Details]
2010 'Analysis of the response of Candida albicans cells to Silver(I)'
Rowan, R;McCann, M;Kavanagh, K (2010) 'Analysis of the response of Candida albicans cells to Silver(I)'. Medical Mycology, 48 :498-505 [DOI] [IR Link] [Details]
2010 'Correlation between Ocular Demodex Infestation and Serum Immunoreactivity to Bacillus Proteins in Patients with Facial Rosacea'
Li, JJ;O'Reilly, N;Sheha, H;Katz, R;Raju, VK;Kavanagh, K;Tseng, SCG (2010) 'Correlation between Ocular Demodex Infestation and Serum Immunoreactivity to Bacillus Proteins in Patients with Facial Rosacea'. Ophthalmology, 117 :870-48 [DOI] [IR Link] [Details]
2010 'Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin'
Fallon, JP;Reeves, EP;Kavanagh, K (2010) 'Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin'. Journal of Medical Microbiology, 59 :625-633 [DOI] [IR Link] [Details]
2010 'Self-Protection against Gliotoxin-A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin'
Schrettl, M;Carberry, S;Kavanagh, K;Haas, H;Jones, GW;O'Brien, J;Nolan, A;Stephens, J;Fenelon, O;Doyle, S (2010) 'Self-Protection against Gliotoxin-A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin'. PLoS Pathogens, 6 [DOI] [IR Link] [Details]
2010 'Dose-dependent cellular and humoral responses in Galleria mellonella larvae following beta-glucan inoculation'
Mowlds, P;Coates, C;Renwick, J;Kavanagh, K (2010) 'Dose-dependent cellular and humoral responses in Galleria mellonella larvae following beta-glucan inoculation'. Microbes and Infection, 12 :146-153 [DOI] [IR Link] [Details]
2009 'Demodex mites in human diseases: Under the lash'
Lacey N.;Kavanagh K.;Tseng S. (2009) 'Demodex mites in human diseases: Under the lash'. Biochemist, 31 (4):20-24 [IR Link] [Details]
2009 'Exposure to caspofungin activates Cap and Hog pathways in Candida albicans'
Kelly, J;Rowan, R;Mccann, M;Kavanagh, K (2009) 'Exposure to caspofungin activates Cap and Hog pathways in Candida albicans'. Medical Mycology, 47 :697-706 [DOI] [IR Link] [Details]
2009 'Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]'
Rowan R.;Moran C.;McCann M.;Kavanagh K. (2009) 'Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]'. BioMetals, 22 (3):461-467 [DOI] [IR Link] [Details]
2008 'Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans'
Mowlds, P;Kavanagh, K (2008) 'Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans'. Mycopathologia, 165 :5-12 [DOI] [IR Link] [Details]
2008 'Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans'
Mowlds, P;Barron, A;Kavanagh, K (2008) 'Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans'. Microbes and Infection, 10 :628-634 [DOI] [IR Link] [Details]
2007 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2] · 8.8H2O and [Cu(4-Mecdoa)(phen)2] · 13H2O (phen = 1,10-phenanthroline)'
Creaven B.;Egan D.;Karcz D.;Kavanagh K.;McCann M.;Mahon M.;Noble A.;Thati B.;Walsh M. (2007) 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2] · 8.8H2O and [Cu(4-Mecdoa)(phen)2] · 13H2O (phen = 1,10-phenanthroline)'. Journal of Inorganic Biochemistry, 101 (8):1108-1119 [DOI] [IR Link] [Details]
2007 'Epsilometer test-based determination of susceptibility of clinically important Candida isolates to conventional antifungal agents'
Abu-Elteen K.;Hamad M.;Kavanagh K. (2007) 'Epsilometer test-based determination of susceptibility of clinically important Candida isolates to conventional antifungal agents'. Journal of Medical Sciences - Pakistan, 7 (3):374-382 [IR Link] [Details]
2007 '[Ag-2(aca)(2)](n) and [Ag-4(aca)(4)(NH3)(2)] (acaH=9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities'
Curran, R;Lenehan, J;McCann, M;Kavanagh, K;Devereux, M;Egan, DA;Clifford, G;Keane, K;Creaven, BS;Mckee, V (2007) '[Ag-2(aca)(2)](n) and [Ag-4(aca)(4)(NH3)(2)] (acaH=9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities'. Inorganic Chemistry Communication, 10 :1149-1153 [DOI] [IR Link] [Details]
2007 'Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans'
Thati, B;Noble, A;Rowan, R;Creaven, BS;Walsh, M;McCann, M;Egan, D;Kavanagh, K (2007) 'Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans'. Toxicology in Vitro, 21 :801-808 [DOI] [IR Link] [Details]
2007 'Mite-related bacterial antigens stimulate inflammatory cells in rosacea'
Lacey, N;Delaney, S;Kavanagh, K;Powell, FC (2007) 'Mite-related bacterial antigens stimulate inflammatory cells in rosacea'. British Journal of Dermatology, 157 :474-481 [DOI] [IR Link] [Details]
2007 'Translocation of proteins homologous to human neutrophil p47(phox) and p67(phox) to the cell membrane in activated hemocytes of Galleria mellonella'
Renwick, J;Reeves, EP;Wientjes, FB;Kavanagh, K (2007) 'Translocation of proteins homologous to human neutrophil p47(phox) and p67(phox) to the cell membrane in activated hemocytes of Galleria mellonella'. Developmental and Comparative Immunology, 31 :347-359 [DOI] [IR Link] [Details]
2007 'Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus'
Vickers, I;Reeves, EP;Kavanagh, KA;Doyle, S (2007) 'Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus'. Protein Expression and Purification, 53 :216-224 [DOI] [IR Link] [Details]
2007 'Synthesis and structure of metal complexes containing zwitterionic N-hydroxyimidazole ligands'
Abuskhuna, S;McCann, M;Briody, J;Devereux, M;Kavanagh, K;Kayal, N;McKee, V (2007) 'Synthesis and structure of metal complexes containing zwitterionic N-hydroxyimidazole ligands'. Polyhedron, 26 :4573-4580 [DOI] [IR Link] [Details]
2007 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH(2)) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH(2)): X-ray crystal structures of [Cu(cdoa)(phen)(2)] center dot 8.8H(2)O and [Cu(4-Mecdoa)(phen)(2)] center dot 13H(2)O (phen=1,10-phenanthroline)'
Creaven, BS;Egan, DA;Karcz, D;Kavanagh, K;McCann, M;Mahon, M;Noble, A;Thati, B;Walsh, M (2007) 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH(2)) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH(2)): X-ray crystal structures of [Cu(cdoa)(phen)(2)] center dot 8.8H(2)O and [Cu(4-Mecdoa)(phen)(2)] center dot 13H(2)O (phen=1,10-phenanthroline)'. Journal of Inorganic Biochemistry, 101 :1108-1119 [DOI] [IR Link] [Details]
2007 'In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines'
Thati B.;Noble A.;Creaven B.;Walsh M.;McCann M.;Kavanagh K.;Devereux M.;Egan D. (2007) 'In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines'. Cancer Letters, 248 (2):321-331 [DOI] [Details]
2007 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells'
Thati B.;Noble A.;Creaven B.;Walsh M.;McCann M.;Kavanagh K.;Devereux M.;Egan D. (2007) 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells'. Cancer Letters, 250 (1):128-139 [DOI] [Details]
2006 'Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin'
Reeves, EP;Nagl, M;O'Keeffe, J;Kelly, J;Kavanagh, K (2006) 'Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin'. Journal of Medical Microbiology, 55 :913-918 [DOI] [IR Link] [Details]
2006 'Susceptibility of larvae of Galleria mellonella to infection by Aspergillus fumigatus is dependent upon stage of conidial germination'
Renwick, J;Daly, P;Reeves, EP;Kavanagh, K (2006) 'Susceptibility of larvae of Galleria mellonella to infection by Aspergillus fumigatus is dependent upon stage of conidial germination'. Mycopathologia, 161 :377-384 [DOI] [IR Link] [Details]
2006 'A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus'
Reeves, EP;Reiber, K;Neville, C;Scheibner, O;Kavanagh, K;Doyle, S (2006) 'A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus'. FEBS Journal, 273 :3038-3053 [DOI] [IR Link] [Details]
2006 'Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides'
Bergin, D;Murphy, L;Keenan, J;Clynes, M;Kavanagh, K (2006) 'Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides'. Microbes and Infection, 8 :2105-2112 [DOI] [IR Link] [Details]
2006 'Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes'
Creaven, BS;Egan, DA;Kavanagh, K;McCann, M;Noble, A;Thati, B;Walsh, M (2006) 'Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes'. Inorganica Chimica Acta, 359 :3976-3984 [DOI] [IR Link] [Details]
2006 ''Silver bullets' in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes'
Rowan, R;Tallon, T;Sheahan, AM;Curran, R;McCann, M;Kavanagh, K;Devereux, M;McKee, V (2006) ''Silver bullets' in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes'. Polyhedron, 25 :1771-1778 [DOI] [IR Link] [Details]
2006 'Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity'
Carberry, S;Neville, CM;Kavanagh, KA;Doyle, S (2006) 'Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity'. Biochemical and Biophysical Research Communications, 341 :1096-1104 [DOI] [IR Link] [Details]
2005 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc) 2(H2O)2] · 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)'
Creaven B.;Egan D.;Kavanagh K.;McCann M.;Mahon M.;Noble A.;Thati B.;Walsh M. (2005) 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc) 2(H2O)2] · 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 (8):949-957 [DOI] [IR Link] [Details]
2005 'A 4 '-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'
Neville, C;Murphy, A;Kavanagh, K;Doyle, S (2005) 'A 4 '-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'. ChemBioChem, 6 :679-685 [DOI] [IR Link] [Details]
2005 'Superoxide production in Galleria mellonella hemocytes: Identification of proteins homologous to the NADPH oxidase complex of human neutrophils'
Bergin, D;Reeves, EP;Renwick, J;Wientjes, FB;Kavanagh, K (2005) 'Superoxide production in Galleria mellonella hemocytes: Identification of proteins homologous to the NADPH oxidase complex of human neutrophils'. Infection and Immunity, 73 :4161-4170 [DOI] [IR Link] [Details]
2005 'Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus'
Burns, C;Geraghty, R;Neville, C;Murphy, A;Kavanagh, K;Doyle, S (2005) 'Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus'. Fungal Genetics and Biology, 42 :319-327 [DOI] [IR Link] [Details]
2005 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)(2)(H2O)(2)] center dot 2H(2)O and [Ag(hnc)] (hncH=4-hydroxy-3-nitro-2H-chromen-2-one)'
Creaven, BS;Egan, DA;Kavanagh, K;McCann, M;Mahon, M;Noble, A;Thati, B;Walsh, M (2005) 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)(2)(H2O)(2)] center dot 2H(2)O and [Ag(hnc)] (hncH=4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 :949-957 [DOI] [IR Link] [Details]
2005 'The expression of selected non-ribosornal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'
Reiber, K;Reeves, EP;Neville, CM;Winkler, R;Gebhardt, P;Kavanagh, K;Doyle, S (2005) 'The expression of selected non-ribosornal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'. Fems Microbiology Letters, 248 :83-91 [DOI] [IR Link] [Details]
2005 'The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'
Reiber K.;Reeves E.;Neville C.;Winkler R.;Gebhardt P.;Kavanagh K.;Doyle S. (2005) 'The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'. Fems Microbiology Letters, 248 (1):83-91 [DOI] [IR Link] [Details]
2004 'Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands'
Abuskhuna, S;Briody, J;McCann, M;Devereux, M;Kavanagh, K;Fontecha, JB;McKee, V (2004) 'Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands'. Polyhedron, 23 :1249-1255 [DOI] [IR Link] [Details]
2004 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4′-thiazolyl)benzimidazole{thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl·H 2O·EtOH and TBZH2NO3 (TBZH=thiabendazole)'
Devereux M.;McCann M.;Shea D.;Kelly R.;Egan D.;Deegan C.;Kavanagh K.;McKee V.;Finn G. (2004) 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4′-thiazolyl)benzimidazole{thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl·H 2O·EtOH and TBZH2NO3 (TBZH=thiabendazole)'. Journal of Inorganic Biochemistry, 98 (6):1023-1031 [DOI] [IR Link] [Details]
2004 'Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus'
Reeves, EP;Murphy, T;Daly, P;Kavanagh, K (2004) 'Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus'. Journal of Medical Microbiology, 53 :719-725 [DOI] [IR Link] [Details]
2004 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4 '-thiazolyl)benzimidazole thiabendazole: X-ray crystal structures of [Cu(TBZH)(2)Cl]C1 center dot H2O center dot. EtOH and TBZH(2)NO(3) (TBZH = thiabendazole)'
Devereux, M;McCann, M;Shea, DO;Kelly, R;Egan, D;Deegan, C;Kavanagh, K;McKee, V;Finn, G (2004) 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4 '-thiazolyl)benzimidazole thiabendazole: X-ray crystal structures of [Cu(TBZH)(2)Cl]C1 center dot H2O center dot. EtOH and TBZH(2)NO(3) (TBZH = thiabendazole)'. Journal of Inorganic Biochemistry, 98 :1023-1031 [DOI] [IR Link] [Details]
2004 'Synthesis and X-ray crystal structure of [Ag(phendio)(2)]ClO4 (phendio=1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells'
McCann, M;Coyle, B;McKay, S;McCormack, P;Kavanagh, K;Devereux, M;McKee, V;Kinsella, P;O'Connor, R;Clynes, M (2004) 'Synthesis and X-ray crystal structure of [Ag(phendio)(2)]ClO4 (phendio=1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells'. BioMetals, 17 :635-645 [IR Link] [Details]
2004 'Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes'
Coyle, B;Kinsella, P;McCann, M;Devereux, M;O'Connor, R;Clynes, M;Kavanagh, K (2004) 'Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes'. Toxicology in Vitro, 18 :63-70 [DOI] [IR Link] [Details]
2004 'Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole'
Eshwika, A;Coyle, B;Devereux, M;McCann, M;Kavanagh, K (2004) 'Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole'. BioMetals, 17 :415-422 [IR Link] [Details]
2004 'Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella'
Reeves, EP;Messina, CGM;Doyle, S;Kavanagh, K (2004) 'Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella'. Mycopathologia, 158 :73-79 [IR Link] [Details]
2004 'Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development'
Fox, M;Gray, G;Kavanagh, K;Lewis, C;Doyle, S (2004) 'Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development'. Journal of Microbiological Methods, 56 :221-230 [DOI] [IR Link] [Details]
2004 'Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag-2(NH3)(2)(salH)(2)] (salH(2)= salicylic acid)'
Coyle, B;McCann, M;Kavanagh, K;Devereux, M;McKee, V;Kayal, N;Egan, D;Deegan, C;Finn, GJ (2004) 'Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag-2(NH3)(2)(salH)(2)] (salH(2)= salicylic acid)'. Journal of Inorganic Biochemistry, 98 :1361-1366 [DOI] [IR Link] [Details]
2003 'Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B'
O'Keeffe, J;Doyle, S;Kavanagh, K (2003) 'Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B'. Journal of Pharmacy and Pharmacology, 55 :1629-1633 [DOI] [IR Link] [Details]
2003 'Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B'
Geraghty, P;Kavanagh, K (2003) 'Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B'. Archives of Microbiology, 179 :295-300 [DOI] [IR Link] [Details]
2003 'Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres'
Deegan, O;Walshe, K;Kavanagh, K;Doyle, S (2003) 'Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres'. Analytical Biochemistry, 312 :175-181 [IR Link] [Details]
2003 'Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans'
Geraghty, P;Kavanagh, K (2003) 'Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans'. Journal of Pharmacy and Pharmacology, 55 :179-184 [DOI] [IR Link] [Details]
2003 'Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes'
Coyle, B;Kavanagh, K;McCann, M;Devereux, M;Geraghty, M (2003) 'Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes'. BioMetals, 16 :321-329 [IR Link] [Details]
2003 'Isolation and identification of Madurella mycetomatis from two cases of black grain mycetoma in Libya'
Ellabib, MS;Refaai, A;Khalifa, Z;Kavanagh, K (2003) 'Isolation and identification of Madurella mycetomatis from two cases of black grain mycetoma in Libya'. Mycoses, 46 :339-341 [IR Link] [Details]
2003 'Synthesis and antimicrobial activity of (Z)-3-(1H-imidazol-1-yl)-2-phenylpropenenitrile and its metal complexes: X-ray crystal structures of the Zn(II) and Ag(I) complexes'
McCann, M;Coyle, B;Briody, J;Bass, F;O'Gorman, N;Devereux, M;Kavanagh, K;McKee, V (2003) 'Synthesis and antimicrobial activity of (Z)-3-(1H-imidazol-1-yl)-2-phenylpropenenitrile and its metal complexes: X-ray crystal structures of the Zn(II) and Ag(I) complexes'. Polyhedron, 22 :1595-1601 [DOI] [IR Link] [Details]
2003 'Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella'
Bergin, D;Brennan, M;Kavanagh, K (2003) 'Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella'. Microbes and Infection, 5 :1389-1395 [DOI] [IR Link] [Details]
2002 'Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study'
Ellabib, MS;Agaj, M;Khalifa, Z;Kavanagh, K (2002) 'Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study'. British Journal of Dermatology, 146 :1038-1041 [IR Link] [Details]
2002 'Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya'
Ellabib, MS;Khalifa, Z;Kavanagh, K (2002) 'Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya'. Mycoses, 45 :101-104 [IR Link] [Details]
2002 'Immobilization of Aspergillus fumigatus colonies in a soft agar matrix allows visualization of A549 cell detachment and death'
Daly, P;Kavanagh, K (2002) 'Immobilization of Aspergillus fumigatus colonies in a soft agar matrix allows visualization of A549 cell detachment and death'. Medical Mycology, 40 :27-33 [IR Link] [Details]
2002 'Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae'
Brennan, M;Thomas, DY;Whiteway, M;Kavanagh, K (2002) 'Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae'. FEMS Immunology and Medical Microbiology, 34 :153-157 [IR Link] [Details]
2002 'Trichophyton violaceum is the dominant cause of tinea capitis in children in Tripoli, Libya: Results of a two year survey'
Ellabib, MS;Agaj, M;Khalifa, Z;Kavanagh, K (2002) 'Trichophyton violaceum is the dominant cause of tinea capitis in children in Tripoli, Libya: Results of a two year survey'. Mycopathologia, 153 :145-147 [IR Link] [Details]
2001 'Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection'
Ennis, O;Corcoran, A;Kavanagh, K;Mahon, BP;Doyle, S (2001) 'Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection'. Journal of Clinical Virology, 22 :55-60 [IR Link] [Details]
2001 'Pulmonary aspergillosis: Clinical presentation, diagnosis and therapy'
Daly P.;Kavanagh K. (2001) 'Pulmonary aspergillosis: Clinical presentation, diagnosis and therapy'. British Journal of Biomedical Science, 58 (3):197-205 [IR Link] [Details]
2001 'Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells'
Murphy A.;Kavanagh K. (2001) 'Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells'. Medical Mycology, 39 (1):123-127 [IR Link] [Details]
2001 'Adherence of clinical isolated of Saccharomyces cerevisiae to buccal epithelial cells'
Murphy, AR;Kavanagh, KA (2001) 'Adherence of clinical isolated of Saccharomyces cerevisiae to buccal epithelial cells'. Medical Mycology, 39 :123-127 [IR Link] [Details]
2000 'Development of an insect model for the in vivo pathogenicity testing of yeasts'
Cotter, G;Doyle, S;Kavanagh, K (2000) 'Development of an insect model for the in vivo pathogenicity testing of yeasts'. FEMS Immunology and Medical Microbiology, 27 :163-169 [IR Link] [Details]
2000 'Adherence mechanisms of Candida albicans'
Cotter G.;Kavanagh K. (2000) 'Adherence mechanisms of Candida albicans'. British Journal of Biomedical Science, 57 (3):241-249 [IR Link] [Details]
1999 'Characterisation of yeasts implicated in vulvovaginal candidosis in Irish women'
Al-Rawi, N;Kavanagh, K (1999) 'Characterisation of yeasts implicated in vulvovaginal candidosis in Irish women'. British Journal of Biomedical Science, 56 :99-104 [Details]
1999 'Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines'
Daly, P;Verhaegen, S;Clynes, M;Kavanagh, K (1999) 'Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines'. Mycopathologia, 146 :67-74 [IR Link] [Details]
1998 'Monoclonal antibodies directed against extracellular matrix proteins reduce the adherence of Candida albicans to HEp-2 cells'
Cotter, G;Weedle, R;Kavanagh, K (1998) 'Monoclonal antibodies directed against extracellular matrix proteins reduce the adherence of Candida albicans to HEp-2 cells'. Mycopathologia, 141 :137-142 [IR Link] [Details]
1998 'A rapid method for the extraction of whole cell proteins from Candida species'
Al-Rawi, N;Kavanagh, K (1998) 'A rapid method for the extraction of whole cell proteins from Candida species'. Journal of Microbiological Methods, 34 :107-112 [IR Link] [Details]
1997 'Membrane changes associated with the early stages of apoptosis in HEp-2 cells decrease susceptibility adherence by Candida albicans'
Cotter, G;Verhaegen, S;Clynes, M;Kavanagh, K (1997) 'Membrane changes associated with the early stages of apoptosis in HEp-2 cells decrease susceptibility adherence by Candida albicans'. Journal of Medical and Veterinary Mycology, 35 :219-224 [IR Link] [Details]
1996 'Application of protoplast fusion to the nonconventional yeast'
Kavanagh, K;Whittaker, PA (1996) 'Application of protoplast fusion to the nonconventional yeast'. Enzyme and Microbial Technology, 18 :45-51 [IR Link] [Details]
1994 'APPLICATION OF THE MELLE-BOINOT PROCESS TO THE FERMENTATION OF XYLOSE BY PACHYSOLEN-TANNOPHILUS'
KAVANAGH, K;WHITTAKER, PA (1994) 'APPLICATION OF THE MELLE-BOINOT PROCESS TO THE FERMENTATION OF XYLOSE BY PACHYSOLEN-TANNOPHILUS'. Applied Microbiology and Biotechnology, 42 :28-31 [Details]
1994 'ANALYSIS OF HYBRIDS OF CANDIDA-ALBICANS FORMED BY PROTOPLAST FUSION'
LAW, C;KAVANAGH, K;WHITTAKER, P (1994) 'ANALYSIS OF HYBRIDS OF CANDIDA-ALBICANS FORMED BY PROTOPLAST FUSION'. Fems Microbiology Letters, 115 :77-82 [IR Link] [Details]
1992 'A NOVEL TECHNIQUE FOR STUDYING THE ADHERENCE OF CANDIDA-ALBICANS TO HEP-2 CELLS'
KAVANAGH, K;WEEDLE, R;GHANNOUM, M;WHITTAKER, P (1992) 'A NOVEL TECHNIQUE FOR STUDYING THE ADHERENCE OF CANDIDA-ALBICANS TO HEP-2 CELLS'. Journal of Microbiological Methods, 16 :39-46 [Details]
1992 'MULTIPLE TRANSFORMATION OF SACCHAROMYCES-CEREVISIAE BY PROTOPLAST FUSION'
REEVES, E;KAVANAGH, K;WHITTAKER, PA (1992) 'MULTIPLE TRANSFORMATION OF SACCHAROMYCES-CEREVISIAE BY PROTOPLAST FUSION'. Fems Microbiology Letters, 99 :193-197 [IR Link] [Details]
1991 'ENHANCED INTRASPECIFIC PROTOPLAST FUSION IN YEAST'
KAVANAGH, K;WALSH, M;WHITTAKER, PA (1991) 'ENHANCED INTRASPECIFIC PROTOPLAST FUSION IN YEAST'. Fems Microbiology Letters, 81 :283-286 [IR Link] [Details]
1991 'FUNCELASE - AN EFFICIENT PREPARATION FOR THE ISOLATION OF REVERSION COMPETENT PROTOPLASTS FROM YEASTS'
KAVANAGH, K;WHITTAKER, PA (1991) 'FUNCELASE - AN EFFICIENT PREPARATION FOR THE ISOLATION OF REVERSION COMPETENT PROTOPLASTS FROM YEASTS'. Biotechnology Techniques, 5 :313-316 [IR Link] [Details]
1990 'FORMATION OF SPHEROPLASTS AND PROTOPLASTS IN THE XYLOSE-FERMENTING YEAST PACHYSOLEN-TANNOPHILUS'
KAVANAGH, K;WHITTAKER, PA (1990) 'FORMATION OF SPHEROPLASTS AND PROTOPLASTS IN THE XYLOSE-FERMENTING YEAST PACHYSOLEN-TANNOPHILUS'. Biotechnology and Applied Biochemistry, 12 :57-62 [Details]
2012 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'
A. Eshwika, J. Kelly, J. P. Fallon and K. Kavanagh (2012) 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'. MEDICAL MYCOLOGY, 50 [IR Link] [Details]
2011 'Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity'
Griffith D.M., Duff B, Suponitsky K., Kavanagh K., Morgan M.P., Egan D. and Marmion C.J. (2011) 'Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity'. JOURNAL OF INORGANIC BIOCHEMISTRY   , 105 :793-799 [IR Link] [Details]
2005 'A 4’-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'
Neville, C., Murphy, A., Kavanagh, K.  and Doyle S. (2005) 'A 4’-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'. CHEMBIOCHEM, 6 :679-685 [IR Link] [Details]
2004 'Metal-complexes of 1, 10 phenanthroline-5,6-dione alter the susceptibility of the yeast  Candida albicans to Amphotericin B and Miconazole'
Eshwika, A., Coyle, B, Devereux, M,  McCann, M. and  Kavanagh, K. (2004) 'Metal-complexes of 1, 10 phenanthroline-5,6-dione alter the susceptibility of the yeast  Candida albicans to Amphotericin B and Miconazole'. BIOMETALS, 17 :415-422 [IR Link] [Details]

Conference Contributions

  Year Publication
2001 British Society for Medical Mycology.
M. Brennan, G. Cotter (2001) British Society for Medical Mycology. Imperial College, London , 04-JAN-01 - 04-MAR-01 [Details]

Article

  Year Publication
2012 Galleria mellonella as a model for fungal pathogenicity testing.
Fallon J.;Kelly J.;Kavanagh K. (2012) Galleria mellonella as a model for fungal pathogenicity testing. Article [DOI] [IR Link] [Details]

Editorial

  Year Publication
2013 Developing the potential of using Galleria mellonella larvae as models for studying brain infection by Listeria monocytogenes.
Browne, N;Kavanagh, K (2013) Developing the potential of using Galleria mellonella larvae as models for studying brain infection by Listeria monocytogenes. AUSTIN: Editorial [DOI] [Details]
2007 Preface.
Kavanagh K. (2007) Preface. Editorial [DOI] [Details]

Magazine Article

  Year Publication
2017 Design and synthesis of small molecule inhibitors bearing 1,2,3-triazole/sulfonate pharmacophore from natural precursors for the treatment of bacterial infections.
Aneja, B;Alam, S;Azam, M;Perwez, A;Haque, R;Rizvi, M;Maguire, R;Kavanagh, K;Yadava, U;Daniliuc, C;Azam, A;Mohammad, A (2017) Design and synthesis of small molecule inhibitors bearing 1,2,3-triazole/sulfonate pharmacophore from natural precursors for the treatment of bacterial infections. WASHINGTON: Magazine Article [Details]
2017 Estrogens-functionalized metal complexes: selective anticancer and antibacterial activity.
Montagner, D;Erxleben, A;Miguel, PS;Kavanagh, K;Kellett, A (2017) Estrogens-functionalized metal complexes: selective anticancer and antibacterial activity. NEW YORK: Magazine Article [Details]
2017 Diketo acids and their hybrid bioisoster derivatives as bacterial biofilm and Methionine Aminopeptidase (MetAP) inhibitors.
Mohammad, A;Hasan, P;Pillalamarry, V;Irfan, M;Perwez, A;Ahmad, B;Yadava, U;Rizvi, M;Daniliuc, C;Maguire, R;Kavanagh, K;Addlagatta, A (2017) Diketo acids and their hybrid bioisoster derivatives as bacterial biofilm and Methionine Aminopeptidase (MetAP) inhibitors. WASHINGTON: Magazine Article [Details]
2015 Analysis of the role of Bacillus oleronius proteins in the induction of tissue damage and inflammation in ocular rosacea.
McMahob, F;Gallagher, C;Clynes, M;O'Sullivan, F;Kavanagh, K (2015) Analysis of the role of Bacillus oleronius proteins in the induction of tissue damage and inflammation in ocular rosacea. NEW YORK: Magazine Article [Details]
2014 Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance.
Maurer, E;Browne, N;Surlis, C;Kavanagh, K;Lass-Florl, C;Binder, U (2014) Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance. HOBOKEN: Magazine Article [IR Link] [Details]
2012 Gliotoxin, the Aspergillus fumigatus virulence factor downregulates vitamin D receptor expression and initiates a T-helper 2 response in cystic fibrosis airway disease.
Coughlan, CA;Chotirmall, SH;Bergsson, G;Eshwika, A;Greene, CM;Gunaratnam, C;Kavanagh, K;Reeves, EP;McElvaney, NG (2012) Gliotoxin, the Aspergillus fumigatus virulence factor downregulates vitamin D receptor expression and initiates a T-helper 2 response in cystic fibrosis airway disease. HOBOKEN: Magazine Article [Details]
2011 GLIOTOXIN SECRETION IS RESPONSIBLE FOR VITAMIN D RECEPTOR DOWN-REGULATION AND A HEIGHTENED T-HELPER 2 RESPONSE IN ASPERGILLUS FUMIGATUS COLONISED CYSTIC FIBROSIS AIRWAYS.
Coughlan, CA;Reeves, EP;Bergsson, G;Greene, CM;Chotirmall, SH;Kavanagh, K;McElvaney, NG (2011) GLIOTOXIN SECRETION IS RESPONSIBLE FOR VITAMIN D RECEPTOR DOWN-REGULATION AND A HEIGHTENED T-HELPER 2 RESPONSE IN ASPERGILLUS FUMIGATUS COLONISED CYSTIC FIBROSIS AIRWAYS. MALDEN: Magazine Article [Details]
2010 GLIOTOXIN, A SECONDARY METABOLITE OF ASPERGILLUS FUMIGATUS REGULATES VITAMIN D RECEPTOR EXPRESSION IN CYSTIC FIBROSIS.
Coughlan, C;Reeves, EP;Bergsson, G;Greene, C;Kavanagh, K;O'Neill, SJ;McElvaney, NG (2010) GLIOTOXIN, A SECONDARY METABOLITE OF ASPERGILLUS FUMIGATUS REGULATES VITAMIN D RECEPTOR EXPRESSION IN CYSTIC FIBROSIS. HOBOKEN: Magazine Article [IR Link] [Details]
2008 Antibiotics used in the treatment of rosacea affect proliferation and lipid production in SZ95 cells.
Lacey, N;Kavanagh, K;Seltmann, H;Zouboulis, C;Powell, FC (2008) Antibiotics used in the treatment of rosacea affect proliferation and lipid production in SZ95 cells. MALDEN: Magazine Article [Details]
2005 Induction of apoptosis by novel metal-based derivatives of coumarin.
Thati, B;Egan, DA;Kavanagh, K (2005) Induction of apoptosis by novel metal-based derivatives of coumarin. PHILADELPHIA: Magazine Article [Details]
1988 THE EFFECT OF CELL RECYCLE BATCH FERMENTATION ON ETHANOL-PRODUCTION BY PACHYSOLEN-TANNOPHILUS AND CANDIDA-SHEHATAE.
KAVANAGH, KA;WHITTAKER, PA (1988) THE EFFECT OF CELL RECYCLE BATCH FERMENTATION ON ETHANOL-PRODUCTION BY PACHYSOLEN-TANNOPHILUS AND CANDIDA-SHEHATAE. LONDON: Magazine Article [Details]

Reviews

  Year Publication
2018 Innate humoral immune defences in mammals and insects: The same, with differences ?.
Sheehan, G;Garvey, A;Croke, M;Kavanagh, K (2018) Innate humoral immune defences in mammals and insects: The same, with differences ?. PHILADELPHIA: Reviews [DOI] [Details]
2016 The role of altered cutaneous immune responses in the induction and persistence of rosacea.
Margalit A.;Kowalczyk M.;Zaba R.;Kavanagh K. (2016) The role of altered cutaneous immune responses in the induction and persistence of rosacea. Reviews [DOI] [IR Link] [Details]
2015 The innate immune response to Aspergillus fumigatus at the alveolar surface.
Margalit, A;Kavanagh, K (2015) The innate immune response to Aspergillus fumigatus at the alveolar surface. OXFORD: Reviews [DOI] [IR Link] [Details]
2013 An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes.
Browne, N;Heelan, M;Kavanagh, K (2013) An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes. AUSTIN: Reviews [DOI] [IR Link] [Details]
2012 Potential role of Demodex mites and bacteria in the induction of rosacea.
Jarmuda, S;O'Reilly, N;Zaba, R;Jakubowicz, O;Szkaradkiewicz, A;Kavanagh, K (2012) Potential role of Demodex mites and bacteria in the induction of rosacea. READING: Reviews [DOI] [IR Link] [Details]
2012 Deciphering the Antimicrobial Activity of Phenanthroline Chelators.
McCann, M;Kellett, A;Kavanagh, K;Devereux, M;Santos, ALS (2012) Deciphering the Antimicrobial Activity of Phenanthroline Chelators. SHARJAH: Reviews [Details]
2010 Galleria mellonella larvae as models for studying fungal virulence.
Kavanagh K.;Fallon J. (2010) Galleria mellonella larvae as models for studying fungal virulence. Reviews [DOI] [IR Link] [Details]
2007 Insect and mammalian innate immune responses are much alike.
Kavanagh K.;Reeves E. (2007) Insect and mammalian innate immune responses are much alike. Reviews [IR Link] [Details]
2004 Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens.
Kavanagh, K;Reeves, EP (2004) Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens. AMSTERDAM: Reviews [DOI] [IR Link] [Details]
2004 Histatins: antimicrobial peptides with therapeutic potential.
Kavanagh, K;Dowd, S (2004) Histatins: antimicrobial peptides with therapeutic potential. LONDON: Reviews [DOI] [IR Link] [Details]
2001 Pulmonary aspergillosis: clinical presentation, diagnosis and therapy.
Daly, P;Kavanagh, K (2001) Pulmonary aspergillosis: clinical presentation, diagnosis and therapy. LONDON: Reviews [IR Link] [Details]
2000 Adherence mechanisms of Candida albicans.
Cotter, G;Kavanagh, K (2000) Adherence mechanisms of Candida albicans. LONDON: Reviews [IR Link] [Details]
1999 Emergence of Saccharomyces cerevisiae as a human pathogen Implications for biotechnology.
Murphy, A;Kavanagh, K (1999) Emergence of Saccharomyces cerevisiae as a human pathogen Implications for biotechnology. NEW YORK: Reviews [IR Link] [Details]

Thesis

  Year Publication
2013 Molecular and epidemiological studies of Trichoderma aggressivum.
Matthew O’Brien (2013) Molecular and epidemiological studies of Trichoderma aggressivum. NUIM: Thesis [Details]
2012 Synthesis and characterization of silver(I) bioglues and assessment of biological activity of AgNO3 against Staphylococcus aureus.
Smith, A. (2012) Synthesis and characterization of silver(I) bioglues and assessment of biological activity of AgNO3 against Staphylococcus aureus. NUIM: Thesis [Details]
2012 A comparison of the innate immune responses of humans and insects.
Banville, N (2012) A comparison of the innate immune responses of humans and insects. NUIM: Thesis [Details]
2012 Evaluation of different methods for the detection of Mycobacterium bovis in lymph tissue.
Madigan, G. (2012) Evaluation of different methods for the detection of Mycobacterium bovis in lymph tissue. NUIM: Thesis [Details]
2012 An analysis of the role of Bacillus oleronius in the induction of rosacea.
O'Reilly, N. (2012) An analysis of the role of Bacillus oleronius in the induction of rosacea. NUIM: Thesis [Details]
2011 Functional Genomic Analysis of Natural Product Biosynthesis and Secretion in Aspergillus fumigatus’.
Gallagher, L (2011) Functional Genomic Analysis of Natural Product Biosynthesis and Secretion in Aspergillus fumigatus’. NUIM: Thesis [Details]
2011 In vitro pharmacological and proteomic effects of novel metal-based anti-cancer agents.
Duff, B (2011) In vitro pharmacological and proteomic effects of novel metal-based anti-cancer agents. NUIM & ITT Dublin: Thesis [Details]
2011 A Molecular and Proteomic Investigation of the in Vitro and In Vivo Anti-microbial Efficacy of Novel Silver(I)-Coumarin Compounds.
Tomkins, K (2011) A Molecular and Proteomic Investigation of the in Vitro and In Vivo Anti-microbial Efficacy of Novel Silver(I)-Coumarin Compounds. NUIM & ITT Dublin: Thesis [Details]
2010 Molecular and microbiological methods for the detection and measurement of dry bubble caused by Lecanicillium fungicola on mushroom farms.
Piasecka, J. (2010) Molecular and microbiological methods for the detection and measurement of dry bubble caused by Lecanicillium fungicola on mushroom farms. NUIM: Thesis [Details]
2010 An analysis of the interaction of environmental and clinical isolates of Aspergillus fumigatus with vertebrate and invertebrate immune responses.
Fallon, J. (2010) An analysis of the interaction of environmental and clinical isolates of Aspergillus fumigatus with vertebrate and invertebrate immune responses. NUIM: Thesis [Details]
2008 An analysis of the cellular and humoral immune responses of Galleria mellonella to fungal pathogens.
Mowlds, P. (2008) An analysis of the cellular and humoral immune responses of Galleria mellonella to fungal pathogens. NUIM: Thesis [Details]
2008 An examination of the interaction of caspofungin with the yeast Candida albicans.’.
Kelly, J. (2008) An examination of the interaction of caspofungin with the yeast Candida albicans.’. NUIM: Thesis [Details]
2007 Role of Bacillus oleronius in the induction of papulopustular rosacea.”.
Lacey, N. (2007) Role of Bacillus oleronius in the induction of papulopustular rosacea.”. NUIM: Thesis [Details]
2007 Investigations into the anti-Candida albicans of Silver(I) containing drugs.
Rowan, R. (2007) Investigations into the anti-Candida albicans of Silver(I) containing drugs. NUIM: Thesis [Details]
2007 An investigation of the interaction of Amphotericin B with the human pathogenic yeast Candida albicans.
Corrigan, M. (2007) An investigation of the interaction of Amphotericin B with the human pathogenic yeast Candida albicans. Thesis [Details]
2006 A study of mode of action of novel metal based drugs as antimicrobial and anti-neoplastic agents.
Thati, B (2006) A study of mode of action of novel metal based drugs as antimicrobial and anti-neoplastic agents. NUIM & ITT Dublin: Thesis [Details]
2006 Analysis of insect immune response to Aspergillus fumigatus.
Renwick, J. (2006) Analysis of insect immune response to Aspergillus fumigatus. NUIM: Thesis [Details]
2005 Analysis of insect immune responses to fungal infection.
Bergin, D. (2005) Analysis of insect immune responses to fungal infection. Thesis [Details]
2004 Identification and characterisation of NRP synthetase and 4’-Phosphopantetheinyl transferase genes within Aspergillus fumigatus”.
Neville, C. (2004) Identification and characterisation of NRP synthetase and 4’-Phosphopantetheinyl transferase genes within Aspergillus fumigatus”. NUIM: Thesis [Details]
2004 An investigation of the role of bacterial and Demodex associated antigens in the induction of Rosacea.
Delaney, S. (2004) An investigation of the role of bacterial and Demodex associated antigens in the induction of Rosacea. NUIM: Thesis [Details]
2004 Metal-based anti-microbial drugs: Synthesis, characterisation and biological testing.
Eshwika, A. (2004) Metal-based anti-microbial drugs: Synthesis, characterisation and biological testing. NUIM: Thesis [Details]
2004 The role of the mitochondrion in fungal pathogenicity.
Geraghty, P (2004) The role of the mitochondrion in fungal pathogenicity. NUIM: Thesis [Details]
2004 An investigation of the interaction of anti-neoplatic agents with yeast drug efflux pumps.
O'Keeffe, J. (2004) An investigation of the interaction of anti-neoplatic agents with yeast drug efflux pumps. NUIM: Thesis [Details]
2002 Elucidation of role of adhesins of Candida albicans.
Maye, L. (2002) Elucidation of role of adhesins of Candida albicans. Thesis [Details]
2002 A study of factors affecting mushroom (Agaricus bisporus) quality, their interaction and control.
Connolly, M. (2002) A study of factors affecting mushroom (Agaricus bisporus) quality, their interaction and control. NUIM: Thesis [Details]
2002 High level expression and characterisation of phytases from genetically modified strains of Aspergillus.
Martin, J. (2002) High level expression and characterisation of phytases from genetically modified strains of Aspergillus. NUIM: Thesis [Details]
2001 An investigation of the virulence factors of clinical isolates of Saccharomyces cerevisiae.
Murphy, A. (2001) An investigation of the virulence factors of clinical isolates of Saccharomyces cerevisiae. NUI M: Thesis [Details]
2001 Development of an insect model for studying fungal pathogenicity.
Brennan, M (2001) Development of an insect model for studying fungal pathogenicity. Thesis [Details]
2000 Characterisation of yeast implicated in vulvovaginal candidosis in Irish women.
Al Rawi, N (2000) Characterisation of yeast implicated in vulvovaginal candidosis in Irish women. NUI: Thesis [Details]
1999 A study of the effects of anti-neoplastic agents on the virulence of Candida albicans.
Cotter, G (1999) A study of the effects of anti-neoplastic agents on the virulence of Candida albicans. NUI: Thesis [Details]
1999 A study of the interaction of Aspergillus fumigatus virulence factors with human cancer cell lines.
Daly, P (1999) A study of the interaction of Aspergillus fumigatus virulence factors with human cancer cell lines. NUI: Thesis [Details]