Dr Jennifer McManus

Chemistry

Head of Department

MAP Lodge
3
(01) 7086926

Biography

  • Head of Department, Department of Chemistry (July 2017 - present)
  • Senior Lecturer, Department of Chemistry (2016 - present)
  • Visiting Scholar, Department of Physics, Harvard University (Feb - April 2016)
  • Lecturer, Department of Chemistry (2013-2016)
  • Science Foundation Ireland Stokes Lecturer, Department of Chemistry, Maynooth University (2008-2013)
  • Postdoctoral Associate, Massachusetts Institute of Technology (2005-2008)
  • Postdoctoral Fellow, Department of Physics, University of Fribourg, Switzerland (2004)
  • Visiting Student, Max Planck Institute for Polymer Research, Mainz, Germany (2001)
  • Ph.D., Department of Chemistry, University College Dublin (2003)

Research Interests

  • Protein condensation and phase diagrams
  • Self-assembly of soft materials
  • Protein aggregation
  • Mechanical properties of soft materials and biological tissue
  • Bottom up approaches to synthetic biology
  • Membrane protein crystallization

Peer Reviewed Journals

  Year Publication
2017 'Protein self-assembly following in-situ expression in artificial and mammalian cells'
Urszula M. Migas, Michelle K. Quinn, Jennifer J. McManus (2017) 'Protein self-assembly following in-situ expression in artificial and mammalian cells'. Integrative Biology, DOI: 10.1039/C6IB00240D [DOI] [Details]
2017 'The Mechanical Properties of Individual Cell Spheroids'
Alice Blumlein, Noel Williams, Jennifer J. McManus (2017) 'The Mechanical Properties of Individual Cell Spheroids'. Scientific Reports, 7 (7346) [DOI] [Details]
2017 'Stabilising effect of α-lactalbumin on concentrated infant milk formula emulsions heat treated pre- or post-homogenisation'
Aoife K. Buggy, Jennifer J. McManus, André Brodkorb, Noel Mc Carthy, Mark A. Fenelon (2017) 'Stabilising effect of α-lactalbumin on concentrated infant milk formula emulsions heat treated pre- or post-homogenisation'. Dairy Science and Technology, 96 :845-859 [DOI] [Details]
2016 'The Physics of Protein Self-Assembly'
Jennifer J. McManus, Patrick Charbonneau, Emanuela Zaccarelli, Neer Asherie (2016) 'The Physics of Protein Self-Assembly'. Current Opinion in Colloid and Interface Science, 22 :73-79 [DOI] [Details]
2015 'The self assembly of proteins; Probing patchy protein interactions'
Susan James, Michelle K. Quinn, Jennifer J. McManus (2015) 'The self assembly of proteins; Probing patchy protein interactions'. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 17 :5413-5420 [DOI] [IR Link] [Details]
2015 'Bigel formation via spinodal decomposition of unfolded protein'
Alice Blumlein and Jennifer J. McManus* (2015) 'Bigel formation via spinodal decomposition of unfolded protein'. Journal of Materials Chemistry B, DOI: 10.1039/C5TB00131E [Details]
2015 'How Fluorescent labelling alters the solution behavior of proteins'
Michelle K. Quinn, Nicoletta Gnan, Susan James, Andrea Ninarello, Francesco Sciortino, Emanuela Zaccarelli, Jennifer J. McManus* (2015) 'How Fluorescent labelling alters the solution behavior of proteins'. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, DOI: 10.1039/C5CP04463D [DOI] [IR Link] [Details]
2014 'Simultaneous measurement of a range of particle sizes during A beta 1-42 fibrillogenesis quantified using fluorescence correlation spectroscopy'
Mittag J.;Milani S.;Walsh D.;Raedler J.;McManus J. (2014) 'Simultaneous measurement of a range of particle sizes during A beta 1-42 fibrillogenesis quantified using fluorescence correlation spectroscopy'. Biochemical and Biophysical Research Communications, 448 (2):195-199 [DOI] [IR Link] [Details]
2014 'Adding glycolipid functionality to model membranes-phase behaviour of a synthetic glycolipid in a phospholipid membrane'
Urszula M. Migas, Lorna Abbey, Trinidad Velasco-Torrijos, Jennifer J. McManus* (2014) 'Adding glycolipid functionality to model membranes-phase behaviour of a synthetic glycolipid in a phospholipid membrane'. Soft Matter, 10 :3978-3983 [DOI] [IR Link] [Details]
2013 'Reversible and non-reversible thermal denaturation of lysozyme with varying pH at low ionic strength'
Blumlein Alice, McManus Jennifer J.* (2013) 'Reversible and non-reversible thermal denaturation of lysozyme with varying pH at low ionic strength'. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1834 :2064-2070 [IR Link] [Details]
2013 'Protein corona mediates impact of nanomaterials and slows amyloid beta fibrillation (COVER)'
Mahmoudi M. *, M. P. Monopoli, M. Rezaei, I. Lynch, F. Bertoli, J. J. McManus*, K.A. Dawson* (2013) 'Protein corona mediates impact of nanomaterials and slows amyloid beta fibrillation (COVER)'. CHEMBIOCHEM, 14 :568-572 [Details]
2012 'Differing modes of interaction between monomeric Aβ 1-40 peptides and model lipid membranes: An AFM study'
Sheikh K.;Giordani C.;McManus J.;Hovgaard M.;Jarvis S. (2012) 'Differing modes of interaction between monomeric Aβ 1-40 peptides and model lipid membranes: An AFM study'. Chemistry and Physics of Lipids, 165 (2):142-150 [DOI] [IR Link] [Details]
2012 'Thermal and solution stability of lysozyme in the presence of sucrose, glucose and trehalose'
Susan James and Jennifer J. McManus* (2012) 'Thermal and solution stability of lysozyme in the presence of sucrose, glucose and trehalose'. JOURNAL OF PHYSICAL CHEMISTRY B, 116 :10182-10188 [IR Link] [Details]
2011 'Blowing Bubbles to study living material'
Crosby, Alfred J. and McManus, Jennifer J. (2011) 'Blowing Bubbles to study living material'. PHYSICS TODAY, 64 :62-63 [IR Link] [Details]
2011 'Cavitation rheology of the eye lens (COVER)'
J. Cui, C. Hee-Lee, A. Delbos, J. J. McManus*, A. J. Crosby* (2011) 'Cavitation rheology of the eye lens (COVER)'. SOFT MATTER, 7 :7827-7831 [DOI] [IR Link] [Details]
2010 'Phase behavior of mixtures of human lens proteins Gamma D and Beta B1'
Ying Wang, Aleksey Lomakin, Jennifer J. McManus, Olutayo Ogun, George B. Benedek (2010) 'Phase behavior of mixtures of human lens proteins Gamma D and Beta B1'. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, 107 :13282-13287 [IR Link] [Details]
2010 'Cavitation Rheology of the Vitreous: mechanical properties of biological tissue'
Zimberlin, Jessica, Jennifer J. McManus*, Alfred J. Crosby* (2010) 'Cavitation Rheology of the Vitreous: mechanical properties of biological tissue'. SOFT MATTER, 6 :3632-3635 [IR Link] [Details]
2007 'Structure of cholesterol helical ribbons, self-assembling biological springs'
B. Khaykovich, C. Houssain, J. J. McManus, A. Lomakin, D. M. Moncton, G. B. Benedek (2007) 'Structure of cholesterol helical ribbons, self-assembling biological springs'. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, 104 :9656-9660 [IR Link] [Details]
2007 'Altered Phase Diagram Due to a Single Point Mutation in Human Gamma D-Crystallin'
J. J. McManus, A. Lomakin, A. Pande, O. Ogun, J. Pande and G.B. Benedek (2007) 'Altered Phase Diagram Due to a Single Point Mutation in Human Gamma D-Crystallin'. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, 104 :16856-16861 [IR Link] [Details]
2004 'Observation of a Rectangular Columnar Phase in a DNA-Calcium-Zwitterionic Lipid Complex'
J. J. McManus, J. O. Rädler, K.A. Dawson (2004) 'Observation of a Rectangular Columnar Phase in a DNA-Calcium-Zwitterionic Lipid Complex'. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126 :15966-15967 [IR Link] [Details]
2003 'Phase Behaviour of DPPC in a DNA-Calcium-Zwitterionic Lipid Complex studied by SAXS'
J. J. McManus, J. O. Rädler, K.A. Dawson (2003) 'Phase Behaviour of DPPC in a DNA-Calcium-Zwitterionic Lipid Complex studied by SAXS'. LANGMUIR, 19 :9630-9637 [IR Link] [Details]
2003 'Does Calcium Turn a Zwitterionic Lipid Cationic?'
J. J. McManus , J. O. Rädler, K. A. Dawson (2003) 'Does Calcium Turn a Zwitterionic Lipid Cationic?'. JOURNAL OF PHYSICAL CHEMISTRY B, 107 :9869-9875 [IR Link] [Details]
2001 'A simple and effective separation and purification procedure for DNA fragments using Dodecyltrimethylammonium bromide'
D.M. McLoughlin, J.O’Brien, J. J. McManus, A.V.Gorelov, K.A. Dawson (2001) 'A simple and effective separation and purification procedure for DNA fragments using Dodecyltrimethylammonium bromide'. BIOSEPARATION, 9 :307-313 [Details]
2000 'DNA complexes with cationic surfactant in mixed solvents: the influence of excess surfactant and salt'
D.M. McLoughlin, J. J. McManus, A.V.Gorelov, K.A. Dawson (2000) 'DNA complexes with cationic surfactant in mixed solvents: the influence of excess surfactant and salt'. :186-191 [Details]